Registration Dossier
Registration Dossier
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EC number: 202-858-3 | CAS number: 100-50-5
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: limited documented publications
Data source
Reference
- Reference Type:
- publication
- Title:
- Range-Finding Toxicity Data: List VI
- Author:
- Smyth, H.F. et al.
- Year:
- 1 962
- Bibliographic source:
- Am. Ind. Hyg. Ass. J. 23, 95-107
Materials and methods
- Principles of method if other than guideline:
- Method: other in vivo eye irritation study
- GLP compliance:
- no
Test material
- Reference substance name:
- Cyclohex-3-ene-1-carbaldehyde
- EC Number:
- 202-858-3
- EC Name:
- Cyclohex-3-ene-1-carbaldehyde
- Cas Number:
- 100-50-5
- Molecular formula:
- C7H10O
- IUPAC Name:
- cyclohex-3-ene-1-carbaldehyde
- Details on test material:
- 4-Cyclohexene-1-carboxaldehyde
Constituent 1
Test animals / tissue source
- Species:
- rabbit
Test system
- Vehicle:
- not specified
- Controls:
- yes
- Duration of treatment / exposure:
- no data
- Observation period (in vivo):
- no data
- Number of animals or in vitro replicates:
- no data
Results and discussion
In vivo
Results
- Irritation parameter:
- other: Corneal injury, grading system: 1 to 10
- Basis:
- mean
- Time point:
- other: no data
- Score:
- 8
- Max. score:
- 10
- Reversibility:
- not specified
Any other information on results incl. tables
Corneal injury score 8 of possible 10
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
