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EC number: 205-585-8 | CAS number: 143-13-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2006
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- The study was conducted according to transpiration method, also called gas saturation method described in OECD 104 and EU A.4 guidelines. The method was very well described. However, all original data were not reported, in particular, the measurements performed with three differents gas flow rates showing no dependence of flow rate on calculated vapour pressures.
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- publication
- Title:
- Vapour pressures and enthalpies of vaporization of a series of the linear n-alkyl acetates
- Author:
- Krasnykh
- Year:
- 2 006
- Bibliographic source:
- Krasnykh, Eugen L.; Verevkin, Sergey P.; Koutek, Bohumir; Doubsky, Jan - Journal of Chemical Thermodynamics, 2006 , vol. 38, p. 717 - 723
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Type of method:
- gas saturation method
- Remarks:
- also called transpiration method (as cited in the publication)
Test material
- Reference substance name:
- Nonyl acetate
- EC Number:
- 205-585-8
- EC Name:
- Nonyl acetate
- Cas Number:
- 143-13-5
- Molecular formula:
- C11H22O2
- IUPAC Name:
- nonyl acetate
- Test material form:
- other: liquid
- Details on test material:
- With the test item Nonyl acetate (as reported in the publication), other samples of n-alkyl actetates C8-C16 were prepared and purified at the Institute of Organic Chemistry and Biochemistry, Academy of Science in Prague. The degree of purity of all samples was controlled using a Hewlett-Packard gas chromatograph 5890 Series II equipped with a flame ionization detector and a Hewlett-Packard 3390A integrator. The carrier gas (nitrogen) flow was 12,1 cm3.s-1. A capillary column HP-5 was used with a column lenth of 30 m, an inside diameter of 0,32 mm, and a film thickness of 0,25 µm. The standard temperature program of the gas chromatography (GC) was T=333K for 180s followed by a heating rate of 0,167K.s-1 to T= 523K. No impurities (greater than mass fraction 0,003) could be detected in the samples used for the vapour pressure measurements.
Constituent 1
Results and discussion
Vapour pressureopen allclose all
- Temp.:
- 20 °C
- Vapour pressure:
- 3.56 Pa
- Temp.:
- 25 °C
- Vapour pressure:
- 5.64 Pa
Any other information on results incl. tables
Results for the vapour pressure p obtained by the transpiration method (as published in the publication) :
Temperature of saturation [T(K)] |
Mass of transferred sample condensed at T = 243 K. [m(mg)] |
Volume of nitrogen used to transfer mass m of sample. VN2(dm3) |
Gas-flow (dm3.h-1) | Vapour pressure at temperature T calculated from m and the residual vapour pressure at T = 243 K [p(Pa)] |
276,7 | 0,41 | 7,78 | 3,56 | 0,7 |
278,7 | 0,38 | 6 | 3,56 | 0,86 |
281,8 | 0,42 | 4,75 | 3,56 | 1,17 |
284,8 | 0,39 | 3,27 | 3,56 | 1,59 |
287,8 | 0,38 | 2,38 | 3,56 | 2,14 |
290,9 | 0,4 | 1,84 | 3,56 | 2,89 |
294 | 0,38 | 1,31 | 3,56 | 3,89 |
297 | 0,38 | 1,01 | 3,56 | 5,04 |
300 | 0,42 | 0,832 | 3,56 | 6,72 |
303,1 | 0,4 | 0,594 | 3,56 | 8,95 |
306,1 | 0,36 | 0,416 | 3,56 | 11,38 |
309,2 | 0,33 | 0,297 | 3,56 | 14,56 |
The calculation results are presented in the following table:
T | P | 1/T | log10(P) |
K | Pa | 1/K | log10 (Pa) |
276,7 | 0,7 | 0,00361402 | -0,15490196 |
278,7 | 0,86 | 0,00358809 | -0,06550155 |
281,8 | 1,17 | 0,00354862 | 0,06818586 |
284,8 | 1,59 | 0,00351124 | 0,20139712 |
287,8 | 2,14 | 0,00347464 | 0,33041377 |
290,9 | 2,89 | 0,00343761 | 0,46089784 |
294 | 3,89 | 0,00340136 | 0,5899496 |
297 | 5,04 | 0,003367 | 0,70243054 |
300 | 6,72 | 0,00333333 | 0,82736927 |
303,1 | 8,95 | 0,00329924 | 0,95182304 |
306,1 | 11,38 | 0,00326691 | 1,05614226 |
309,2 | 14,56 | 0,00323415 | 1,16316137 |
Linear Regression Parameters :
Parameter | Value |
Slope B | -3493,6 |
Intercept A | 12,469 |
Correlation coefficient r | 0,99995 |
Using the equation log P = B*1/T + A, values of vapour pressure at 20°C and 25 °C were calculated.
Applicant's summary and conclusion
- Conclusions:
- Using transpiration method, also called gas saturation method and described in OECD 104 guideline and EU method A.4, vapour pressures of 3,56 Pa at 20°C and 5,64 Pa at 25 °C were calculated for the Nonyl Acetate.
These values were calculated from the regression of 12 individual measurements. - Executive summary:
Vapour pressures of Nonyl acetate at several temperatures were measured using transpiration method, also called gas saturation method and described in OECD 104 guideline and EU method A.4. Thanks to the equation log P = B*1/T + A and the linear regression parameters of 12 individual measurements between 276,7 and 309,2K , the vapour pressures of the test item were calculated as 3,56 Pa at 20°C and 5,64 Pa at 25.0 °C.
The correlation coefficient r being 0.99995, the linear regression is considered very good and the results are considered as valid. No observations were made which might cause doubts concerning the validity of the study outcome.
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