Registration Dossier
Registration Dossier
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EC number: 215-609-9 | CAS number: 1333-86-4
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Distribution of Label after Intragastric Adminstration of Be-labeled Carbon to Weanling and Aged Mice
- Author:
- LeFevre ME and Joel DC
- Year:
- 1 986
- Bibliographic source:
- Distribution of Label after Intragastric Adminstration of Be-labeled Carbon to Weanling and Aged Mice. Poceedings of the Society for Experimental Biology and Medicine 182, 112-119.
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Carbon black
- EC Number:
- 215-609-9
- EC Name:
- Carbon black
- Cas Number:
- 1333-86-4
- Molecular formula:
- C
- IUPAC Name:
- carbon
- Test material form:
- solid: pellets
Constituent 1
- Radiolabelling:
- not specified
- Remarks:
- Be
Test animals
- Species:
- mouse
Administration / exposure
- Route of administration:
- oral: gavage
Results and discussion
Any other information on results incl. tables
Absorption of carbon black from gastro-intestinal tract was low in mice, with only small amount found in Peyer’s patches
Applicant's summary and conclusion
- Conclusions:
- Absorbtion of carbon black via oral exposure route is low
- Executive summary:
Absorbtion of carbon black via oral exposure route is low
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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