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EC number: 204-589-7 | CAS number: 122-99-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Testing of the toxicity of 2-phenoxyethanol to microorganisms yielded an EC10(30 min) of 360 mg/L regarding activated sludge respiration inhibition.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 360 mg/L
Additional information
The inhibiting effect of 2-phenoxyethanol (purity > 99.9 area-%) on oxygen consumption of activated sludge was investigated in an activated sludge respiration inhibition test according to OECD guideline 209 (1993), Annex to EEC Directive 88/302/EEC (1987), ISO Standard 8192-1986 (E, Method B) and EPA OPPTS 850.6800 (1996) at following concentrations: 0, 248, 496 and 1000 mg/L (BASF AG, 2002). After an incubation time of 30 min, the concentration of dissolved oxygen was measured at test start and after 6 min. Effect concentrations (EC20, EC50, EC80) were obtained from graphical interpolation, resulting in EC20, EC50and EC80 values of 620 mg/L, > 1000 mg/L and > 1000 mg/L, respectively. The data was recalculated resulting in a statistical EC10 of 360 mg/L (not reported in the study).
Another key study investigated the toxicity of 2-phenoxyethanol to the bacterium Pseudomonas putida in a bacterial growth inhibition test according to DIN guideline 38412 Part 8 (Sasol Germany GmbH, 1994), with nominal concentrations of 0, 187.5, 375, 750, 1500, 3000 and 6000 mg/L. After 16 h, an EC10 of 410 mg/L and an EC50 of 1494 mg/L was determined.
In a third key study, the toxicity of 2-phenoxyethanol to the bacterium Pseudomonas putida was determined in a bacterial growth inhibition test according to DIN guideline 38412 Part 8, draft (BASF AG, 1989). Growth inhibition was measured at nominal concentrations of 0, 78.13, 156.25, 312.5, 625, 1250, 2500 and 5000 mg/L after 17 hours of incubation, resulting in an EC10 of 318.9 mg/L, an EC50 of 883.3 mg/L and an EC90 of 2129.5 mg/L.
Further, a supporting study examined growth inhibition effects on Pseudomonas putida and aerobic microorganisms with resulting EC50 value of 1650 mg/L. Another study evaluated reduced light output of Photobacterium phosphoreum with an resulting EC50 after 5 minutes of 32.7 mg/L.
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