Registration Dossier
Registration Dossier
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EC number: 700-422-1 | CAS number: 61320-65-8
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
A LLNA/IMDS was carried out in female NMRI mice after epicutaneous application of formulation
containing 0%, 2 %, 10 %, or 50 % of the test item Diazokomponente Rot B for 3 consecutive days
onto both ears of the animals.
Diazokomponente Rot B showed no sensitizing potential in the modified Local Lymph Node Assay (IMDS) in female NMRI mice after dermal application of up to and including a 50 % concentration. Additionally, no indication for a non-specific(irritant) activation by the test item was detected The positive control hexyl cinnamic aldehyde (CAS-No. 101 -86 -0) was functional for each parameter (Bayer 2011)..
Migrated from Short description of key information:
Diazokomponente Rot B showed no sensitizing potential in the modified Local Lymph Node Assay (IMDS)
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
not required
Justification for classification or non-classification
Based on the available data there is no need for classification
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