Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 212-554-2 | CAS number: 826-36-8
Repeated dose toxicity: other routes
Administrative data
- Endpoint:
- short-term repeated dose toxicity: other route
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment
Data source
Reference
- Title:
- Die pharmakologischen Eigenschaften des Triacetonamines
- Author:
- Chodera, A., Frencel, I., Szpunar, K.
- Year:
- 1 964
- Bibliographic source:
- Pharmazeutische Zentralhalle fuer Deutschland, 103, 17-23
Materials and methods
- Principles of method if other than guideline:
- Method: other: no data
- GLP compliance:
- no
Test material
- Reference substance name:
- Automatically generated during migration to IUCLID 6, no data available
- IUPAC Name:
- Automatically generated during migration to IUCLID 6, no data available
- Details on test material:
- IUCLID4 Test substance: other TS
TS-Freetext:
Triacetoneamine hydrochloride
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- other: s.c.
- Duration of treatment / exposure:
- 30 days
- Frequency of treatment:
- once per day
Doses / concentrations
- Remarks:
- Doses / Concentrations:
250 mg/kg bw
- Control animals:
- other: no data specified
- Details on study design:
- Post-exposure period: no data
Results and discussion
Effect levels
- Dose descriptor:
- NOAEL
- Effect level:
- > 250 mg/kg bw/day
- Sex:
- not specified
Target system / organ toxicity
- Critical effects observed:
- not specified
Any other information on results incl. tables
RS-Freetext:
No reduction in body weight. No indications of substance related intoxictation. (no further data given).
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
