Registration Dossier
Registration Dossier
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EC number: 281-161-6 | CAS number: 83877-91-2
Endpoint summary
Administrative data
Description of key information
Additional information
As the rapid hydrolysis is the driving force for the fate and pathways of this substance, the abiotic degradation can be used to demonstrate fast degradation for this substance. This is justified as all decomposition products have been identified (key study on hydrolysis including Tier 3 approach; Brekelmans 2013). The most relevant degradation products (2 -methylpropanol and ethyl acetoacetate) are readily biodegradable and not classified as hazardous to the environment.
Biodegradation of 2-methylpropanol in 20-d BOD test was 72 % of ThOD and 74 % at 28-d OECD 301 D closed bottle test (Waggy et al. 1994). Based on the study by Price et al. (1974), 20-d biodegradation of 2-methylpropanol using non-adapted settled domestic wastewater was 72 % in freshwater at nominal test concentrations of 3, 7 and 10 mg/l.
Ethyl acetoacetate is readily biodegradable based on the closed bottle test results (European Chemicals Bureau 2002). The biodegradation after 28-d was 66 %. After 7 days, 65 % ethyl acetoacetate was degraded and 10-day window was fulfilled.
The third environmentally non-hazardous degradation product (TiO2) is inorganic and insoluble, lacking bioavailability, and therefore not relevant to be considered in CSA.
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