Registration Dossier
Registration Dossier
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EC number: 204-516-9 | CAS number: 122-03-2
Endpoint summary
Administrative data
Description of key information
Skin irritation:The test substance was determined to be non irritating to hairless mice but irritating to rabbit skin. At 4% in petrolatum the test substance produced no irritation in human subjects.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no study available
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Skin irritation:
Test substance applied undiluted to the backs of hairless mice produced no irritating effets (Urbach & Forbes 1972), but was irritating when applied full strength to intact or abraded rabbit skin (Denine 1973). Test substance tested at 4% in petrolatum produced no irritation after a 48 -hr closed-patch test in 25 human subjects (Kligman 1972).
Justification for selection of skin irritation / corrosion endpoint:
Available data.
Justification for classification or non-classification
No sufficient data for classification available.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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