Registration Dossier
Registration Dossier
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EC number: 237-881-8 | CAS number: 14044-65-6
Endpoint summary
Administrative data
Description of key information
Additional information
Tetrahydrofuran-borane is known to readily hydrolize liberating hydrogen, tetrahydrofuran (CAS 109-99-9) and boric acid (CAS 10043-35-3). For both hydrolysis products relevant aquatic toxicity data was gathered from the ECHA dissemination dossier (d.d. 2014 -04 -24) and tabulated below.
Aquatic toxicity data for tetrahydrofuran:
Study |
Species |
Endpoint |
Effect value |
Fish acute toxicity |
P. promelas |
96-h LC50 |
2160 mg/L |
Fish chronic toxicity |
P. promelas |
33 -d NOEC |
216 mg/L |
Aquatic invertebrates acute toxicity |
D. magna |
48-h LC50 |
3485 mg/L* |
Aquatic invertebrates chronic toxicity |
No information available |
- |
- |
Algae acute |
No information available |
- |
- |
Algae chronic |
S. quadricauda |
8 -d EC3** |
3700 mg/L |
* effect value expressed as parts per milion (ppm).
** endpoint expressed as "toxicity threshold concentration (equivalent to EC3)"
Aquatic toxicity data for boric acid:
Study |
Species |
Endpoint |
Effect value |
Fish acute toxicity |
L. limanda (saltwater) |
96-h LC50 |
74 mg/L* |
Fish chronic toxicity |
I. punctatus |
9-d LC10 |
3.5 mg/L** |
Aquatic invertebrates acute toxicity |
H. azteca |
96-h LC50 |
64 mg/L*** |
Aquatic invertebrates chronic toxicity |
D. magna |
21-d NOEC |
6 mg/L**** |
Algae acute |
S. capricornutum |
72-h EC50 |
52.4 mg/L ***** |
Algae chronic |
S. capricornutum |
72-h NOEC |
17.5 mg/L ***** |
* lowest effect concentration of two WoE endpoints for a boric acid (82%) and disodium tetraborate decahydrate (18%) mixture and for disodium tetraborate, anhydrous.
** lowest effect value of a total of 11 WoE endpoints for both boric acid and various boron/borate species.
*** lowest effect concentration of a total of 23 WoE endpoints for both boric acid and various boron/borate species.
**** lowest effect concentration of a total of 10 WoE endpoints for both boric acid and various boron/borate species.
***** lowest effect concentrations from one of two WoE endpoints.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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