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EC number: 231-293-5 | CAS number: 7486-38-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
Results from the corresponding acid of disodium adipate are taken into account for this endpoint. The estimated Koc values for adipic acid, using different accepted calculation methods are 2.4, 5.3 and 21.5, indicating a low potential for adsorption. This is in good agreement with the calculated log Kow values for the dissociated and non-dissociated form of disodium adipate.
Key value for chemical safety assessment
- Koc at 20 °C:
- 21.5
Additional information
A
read-across approach with adipic acid is applied. In aqueous media,
disodium adipate and adipic acid acid dissociate into the corresponding
anion (1,6-hexandioic acid ion) and the sodium ion and hydrogen ion
(proton), respectively. Fate, behavior and the ecotoxicological
properties of adipic acid and its disodium salt are thought to be an
effect of the di-carboxylate ion rather than of the sodium ion or the
hydrogen ion (proton), which are normal constituents in environmental
systems and have no relevant ecotoxic properties in low concentrations.
Therefore a read-across between disodium adipate and adipic acid is
justified. Under environmental relevant pHs, disodium adipate and
its corresponding acid, adipic acid exists predominantly in the
dissociated form, based upon its pKa values. At pH 5 to 9, the substance
will be deprotonated resulting in the corresponding anion. As cationic
substances in particular generally adsorb strongly, an adsorption
potential of the dissociated form of disodium adipate and adipic acid is
not expected. Nevertheless, in order to predict the mobility and fate of
adipic acid in soil and sediments the organic carbon-water partition
coefficient (Koc) is calculated using different estimation methods
following the recommendations of the Guidance document on information
requirements and chemical safety assessment, chapter R.7a: Endpoint
specific guidance document R.7a (ECHA, 2012). Methods for estimating
Koc, based on statistical relationships between Koc and the
octanol/water partition coefficient (Kow) are used for calculation. The
logKow of 0.093 was measured at pH 3.3, whrer the substance exists in
its neutral from. This value is used as a worst-case assumption for
calculation of the adsorption coefficient. Moreover, the Koc is
estimated with the EPI Suite program (v. 3.20) of the U.S. Environmental
Protection Agency. Here, calculations are based upon the molecule
structure using the molecular connectivity method. The estimated Koc
values for adipic acid, using different accepted calculation methods are
2.4, 5.3 and 21.5, indicating a low potential for adsorption. This is in
good agreement with the calculated log Kow values for the dissociated
and non-dissociated form of disodium adipate.
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