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Diss Factsheets
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EC number: 231-842-9 | CAS number: 7758-89-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
- Endpoint:
- fish life cycle toxicity
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Basic data given. Method not in accordance with guideline standards. Test results might have been influenced by oxygen- or temperature fluctuations. Nevertheless, data for reproduction should be considered as supportive.
Data source
Reference
- Reference Type:
- publication
- Title:
- Chronic toxicity of copper to Fathead minnows (Pimephales Promelas, Rafinesque)
- Author:
- Mount D.
- Year:
- 1 968
- Bibliographic source:
- Water Research Vol 2; pp:215-223
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- life cycle test
- GLP compliance:
- no
Test material
- Reference substance name:
- Copper sulfate
- IUPAC Name:
- Copper sulfate
- Details on test material:
- - Name of test material (as cited in study report): copper sulfate; results are given for the metal copper
- Purity: not stated
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test organisms
- Test organisms (species):
- Pimephales promelas
- Details on test organisms:
- TEST ORGANISM
- Common name: Fathead minnow
- Source: Fish were obtained from eggs collected in the ponds at the Newtown hatchery
Study design
- Test type:
- flow-through
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 11 mo
Test conditions
- Hardness:
- 200 mg/L (CaCO3)
- Test temperature:
- 16 - 225.5 °C
- Nominal and measured concentrations:
- A nominal concentration range of 99, 33, 11 and 3.7 µg/L of copper was used.
All concentrations of copper are expressed as µg/L of the metal. - Details on test conditions:
- TEST SYSTEM
- Emybro cups: nylon screen to a 3 in. section of a 2 in. dia. polythylene water hose.
-Fish: Frys are 10-15 mm long and six weeks old at the beginnig of test. No fish were replaced during the test.
- Test vessel: stainless steeel with glass ends
-fill volume: 12 Liter
- Type of flow-through: test water was introduced at one end and drained down a standpipe at the other and of the test chamber
- Renewal rate of test solution (frequency/flow rate): flow through the chambers was 25 ml/min, initially, but this rate was increased several times over 3 months to 85 ml/min
- No. of vessels per concentration (replicates): 2 - Reference substance (positive control):
- no
Results and discussion
Effect concentrations
- Duration:
- 11 mo
- Dose descriptor:
- EC50
- Effect conc.:
- > 14 - < 32 µg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Remarks:
- copper
- Basis for effect:
- reproduction
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.