Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-756-6 | CAS number: 87-60-5
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: very old study with high dose, only secondary literature available.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Studien über die Wirkung der Chloraniline und Chlortoluidine und des salzsauren 5-Chlor-2-toluidins
- Author:
- Lehmann et. al.
- Year:
- 1 933
- Bibliographic source:
- Arch. Hyg. Bakteriol. 110, 12-32
- Reference Type:
- secondary source
- Title:
- BUA Stoffbericht 55: Chlortoluidine (3-Chlor-2-methylanilin, 5-Chlor-2-methylanilin, 3-Chlor-4-methylanilin)
- Author:
- BUA Beratergremium für umweltrelevante Altstoffe
- Year:
- 1 990
- Bibliographic source:
- Verlag Chemie Weinheim 1991
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- no
- Test type:
- fixed dose procedure
Test material
- Reference substance name:
- 3-chloro-o-toluidine
- EC Number:
- 201-756-6
- EC Name:
- 3-chloro-o-toluidine
- Cas Number:
- 87-60-5
- Molecular formula:
- C7H8ClN
- IUPAC Name:
- 3-chloro-2-methylaniline
Constituent 1
Test animals
- Species:
- cat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- occlusive
- Vehicle:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- other: lethal dose
- Effect level:
- 2 100 mg/kg bw
Any other information on results incl. tables
Applikation of 2,1 g/kg of testsubstance on the back skin of a cat. Animal died within 5 days.
Applikation of 2,5 g/kg of testsubstance on the back skin of a cat. Animal died within 1 days.
Applicant's summary and conclusion
- Interpretation of results:
- other: not sufficient for classification
- Remarks:
- Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
