Arsine

Skin sensitisation

Administrative data

Endpoint:

skin sensitisation: in vitro

Data waiving:

other justification

Justification for data waiving:

other:

Cross-reference

Reason / purpose for cross-reference:

data waiving: supporting information

Reference

Endpoint:

flammable gases

Type of information:

experimental study

Adequacy of study:

weight of evidence

Study period:

1989

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Publication in well acknowledged scientific journal

Qualifier:

no guideline followed

Principles of method if other than guideline:

Experiments were done in a closed cylindrical vessel at atmospheric pressure. Mixtures were ignited by fusing a nichrome wire by electric current at the centre of the vessel. Occurrence of explosion was determined from pressure history after ignition.

GLP compliance:

not specified

Parameter:

lower explosion limit

Value:

5.1 % (not further specified)

Parameter:

upper explosion limit

Value:

78 % (not further specified)

Interpretation of results:

Category 1 (flammable gases) based on GHS criteria

Conclusions:

The flammability limit of arsine in air is 5.1%–78%.

Executive summary:

Flammability limits of the substance in air and the dilution effect of nitrogen on the flammability limits were investigated experimentally. Experiments were done in a closed cylindrical vessel at atmospheric pressure. Mixtures were ignited by fusing a nichrome wire by electric current at the center of the vessel. Occurrence of explosion was determined from pressure history after ignition. Solid power deposit on the inner wall was also useful for the decision in the case of arsine test. The flammability limits were determined as follows. The flammability limit of arsine in air is 5.1–78% (Ohtani, 1989).