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EC number: 258-053-2 | CAS number: 52628-03-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
One key 48-hour Daphnia magna immobilization test; a second supporting study was also available.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 68 mg/L
Additional information
The purpose of this study was to evaluate the acute toxicity of the reaction product of 2-
hydroxyethyl methacrylate (HEMA) with polyphosphoric acid (PPA), hereafter refered to as
HEMA Phosphate, to the freshwater cladoceran, Daphnia magna, over a 48-hour exposure
period. The definitive test was conducted with 4 replicate vessels per test level, with 5
daphnids each, exposed to nominal concentrations of 0 (water control), 6.3, 13, 25, 50, and
100 mg HEMA Phosphate/L. The mean measured concentrations were <LLQ (water
control), 6.79, 14.8, 28.3, 55.5, and 105 mg HEMA Phosphate/L. Because the mean measure
concentrations were within 20% of the target concentrations, the acute toxicity values for
HEMA Phosphate with Daphnia magna were determined based on nominal concentrations.
The results were as follows:
• The 24-hour EC50 = 75 mg/L (95% confidence limits not calculable)
• The 48-hour EC50 = 68 mg/L ( 95% confidence limits 64 – 73 mg/L)
• The 48-hour NOEC = 50 mg/L
An earlier study in Daphnia magna demonstrated a 48 -hr EC50 to be >100 mg/L.
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