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EC number: 218-878-0 | CAS number: 2272-11-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 478 µg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 141 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 47.8 µg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 562 µg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 8 020 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 802 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 1 600 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
No substance-specific data are available for monoethanolamine oleate, however read-across from monoethanolamine is used for the assessment to meet the majority of the standard REACH information requirements. Monoethanolamine oleate is the salt of monoethanolamine and oleic acid. As oleic acid is exempted for registration according to Annex V of REACH Directive 2006/121/EC, the focus is only on the monoethanolammonium cation of monoethanolamine oleate (for more details see reporting format for the analogue approach in Appendix A.2). There is a complete set of data available for monoethanolamine. Besides short-term tests on fish, invertebrates and algae also long-term studies are available.
Guideline studies for short- and long-term toxicity are available for freshwater fish. The critical effect concentrations for monoethanolamine are a 96-h LC50 value of 349 mg/L in carp (Cyprinus carpio) (Huels, 1997a) and a 30-d NOEC of 1.2 mg/L in Japanese killifish (Oryzias latipes) (NITE, 2006). After correction for molecular weight, the effect concentrations for monoethanolamine oleate of 1963 mg/L for short-term toxicity and 6.75 mg/L for long-term toxicity in fish will be used in the assessment.
For invertebrates short- and long-term toxicity guideline studies are available for Daphnia magna. The critical effect concentrations for monoethanolamine are a 48-h EC50 value of 65 mg/L (Huels, 1997b) and a 21-d NOEC 0.85 mg/L (NITE, 1996a). After correction for molecular weight, the effect concentrations for monoethanolamine oleate of 366 mg/L for short-term toxicity and 4.78 mg/L for long-term toxicity in daphnids will be used in the assessment.
A growth inhibition guideline study is available for freshwater algae. The critical effect concentrations for monoethanolamine are a 72-h EC50 value of 2.5 mg/L and a 72-h NOEC of 1 mg/L in Pseudokirchneriella subcapitata (NITE, 1996b). After correction for molecular weight, the effect concentrations for monoethanolamine oleate of 14.1 mg/L for short-term toxicity and 5.62 mg/L for long-term toxicity in algae will be used in the assessment.
For the toxicity of microorganisms a respiration inhibition guideline study with domestic activated sludge is available (BASF, 1991). The 30-min EC10 for monoethanolamine is >1,000 mg/L. After correction for molecular weight, an effect concentration for monoethanolamine oleate of >5,624 mg/L for STP microorganism toxicity will be used in the assessment.
Studies with terrestrial organisms are not available. Because the calculated log Kow for monoethanolamine is low (-1.31), it is expected that monoethanolamine, and also the monoethanolamine cation in monoethanolammonium oleate, will mainly partition to the water compartment. Therefore, direct and indirect exposure of the terrestrial compartments is not expected.
Conclusion on classification
Based on Directive 67/548/EEC, results of validated structure activity relationships and expert judgment may also be taken into account where appropriate with regard to classification and labelling of substances.
Based on all available data for daphnids, fish and algae, monoethanolamine oleate need not to be classified according to Directive 67/548/EEC nor for EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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