Registration Dossier
Registration Dossier
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EC number: 240-759-7 | CAS number: 16712-64-4
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.144 mg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.329 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.014 mg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 27.8 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.74 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.074 mg/kg sediment dw
- Extrapolation method:
- assessment factor
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.019 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
All PNECs were derived from studies conducted with the structural analogon of 6 -HNA, 3 -HNA. As results from QSAR modelling showed a higher toxicity of 3 -HNA than of 6 -HNA, it is justified to use the data derived from the studies with 3 -HNA as a worst-case situation for the PNEC calculation of 6 -HNA.
Conclusion on classification
The lowest value which might be relevant for a classification was a NOEC of 7.21 mg/L derived from an algae study with 3 -HNA. As this is far above the trigger value according both for GHS and DSD, there is no need to classify the substance as toxic for the aquatic environment. This applies also for 6 -HNA, as it is justified to use data derived for 3 -HNA for read-across purposes to 6 -HNA, based on their similar physico-chemical properties.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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