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EC number: 807-789-8 | CAS number: 111062-42-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- The experimental start date was 03 Aug 2018, and the experimental completion date was 15 Aug 2018.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Version / remarks:
- 2004
- GLP compliance:
- yes
- Specific details on test material used for the study:
- UVCB; solid matter 41.4%
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 100 mg solid matter/L
- Sampling method: At the end of the exposure period, the replicates were pooled at each concentration before sampling.
- Sample storage conditions before analysis: Samples were stored in a freezer (≤-15°C) until analysis at the analytical laboratory of the Test Facility. - Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION
- Method: Water Accommodated Fraction (WAF) loading rate of 100 mg solid matter/L - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia magna
- Strain/clone: Straus, 1820
- Age at study initiation: less than 24 hours old, from parental daphnids of more than two weeks old
- Source: In-house laboratory culture with a known history - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Hardness:
- 180 mg/L expressed as CaCO3
- Test temperature:
- 20 to 21°C
- pH:
- 7.9
- Dissolved oxygen:
- 8.2 to 8.6 mg/L
- Nominal and measured concentrations:
- Loading: 100 mg solid matter/L
Measured: 16 mg solid matter/L - Details on test conditions:
- TEST SYSTEM
- Test vessel: 60 mL, all-glass
- Type: open
- Aeration: None
- No. of organisms per vessel: 5 per vessel containing 50 mL of test solution
- No. of vessels per concentration: 4
- No. of vessels per control: 4
TEST MEDIUM / WATER PARAMETERS
ISO-medium.
OTHER TEST CONDITIONS
- Adjustment of pH: none
- Photoperiod: A daily photoperiod of 16 hours
EFFECT PARAMETERS MEASURED:
Immobility (including mortality) At 24 hours and at 48 hours
RANGE-FINDING STUDY
- Test concentrations: WAFs prepared at loading rates of 1.0, 10 and 100 mg solid matter/L
- Results used to determine the conditions for the definitive study: Yes - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
- Duration:
- 48 h
- Dose descriptor:
- LL50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- - Mortality of control: No immobility was observed
- Results with reference substance (positive control):
- - Results with reference substance valid?
Yes
- Relevant effect levels: 48h-EC50 was 0.59 mg/L
- Other: The sensitivity of this batch of D. magna was in agreement with the historical data collected at Charles River Den Bosch - Validity criteria fulfilled:
- yes
- Conclusions:
- In conclusion, the 48h-EL50 for Daphnia magna exposed to the test item was >100 mg solid matter/L. The analytically confirmed concentration of dioctyl phosphate in the test solution was 16 mg/L.
- Executive summary:
The acute toxicity to Daphnia of the test item was assessed following OECD 202 under static conditions. Following a range-finding study, a limit test was performed with a WAF of the test item at 100 mg solid matter/L. No mortality or clinical effects were observed in both the control and the WAF during the test period. The 48h-LL50 for Daphnia magna exposed to the test item was >100 mg solid matter/L. The analytically confirmed concentration of dioctyl phosphate in the test solution was 16 mg/L.
Reference
Description of key information
The acute toxicity to Daphnia of the test item was assessed following OECD 202 under static conditions. Following a range-finding study, a limit test was performed with a WAF of the test item at 100 mg solid matter/L. No mortality or clinical effects were observed in both the control and the WAF during the test period. The 48h-LL50 for Daphnia magna exposed to the test item was >100 mg solid matter/L. The analytically confirmed concentration of dioctyl phosphate in the test solution was 16 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
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