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Diss Factsheets
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EC number: 907-706-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to fish, other
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- Data of test chemical
- Justification for type of information:
- Data for the test chemical is from collection of data
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- other: Refer below principle
- Principles of method if other than guideline:
- WoE report is prepared based on long term toxicity to fish study:
WoE 2 and WoE 3 - GLP compliance:
- not specified
- Analytical monitoring:
- no
- Vehicle:
- not specified
- Test organisms (species):
- other: Fish
- Test type:
- semi-static
- Water media type:
- freshwater
- Total exposure duration:
- 28 d
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.134 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: 1st study
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.173 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: 2nd study
- Validity criteria fulfilled:
- not specified
- Conclusions:
- 1. After the exposure of test chemical with fish for 28 days, NOEC was observed at 0.134 mg/l.
2. After the exposure of test chemical with fish for 28 days, NOEC was observed at 0.173 mg/l.
Thus on the basis of above available data, it can be concluded that the test chemical was toxic to fish and classified as aquatic chronic 3 as per the CLP classification criteria. - Executive summary:
Various long term studies available for the test chemical were reviewed to determine the toxic nature of test chemical on the mortality and other long term effect of fish. The studies are as mentioned below:
Based on the prediction, the long term toxicity on fish was predicted for test substance. On the basis of no effects were observed in a semi static freshwater system, the NOEC value for the test substance is estimated to be 0.134 mg/l for fish for 28 days of exposure duration. Based on this value, it can be concluded that the test chemical can be considered as toxic to fish at environmentally relevant concentrations and can be considered to be classified as aquatic chronic 3 category as per the CLP classification criteria.
Similarly in the another study based on the prediction, the long term toxicity on fish was predicted for test substance. On the basis of no effects observed in a freshwater system, the NOEC value for the test substance is estimated to be 0.173 mg/l for fish for 28 days of exposure duration. Based on this value, it can be concluded that the test chemical can be considered as toxic to fish at environmentally relevant concentrations and chemical was readily biodegradable in water thus on that basis it can be considered to be classified as aquatic chronic 3 category as per the CLP classification criteria.
Thus on the basis of above available data, it can be concluded that the test chemical was toxic to fish and classified as aquatic chronic 3 as per the CLP classification criteria.
- Endpoint:
- fish early-life stage toxicity
- Data waiving:
- other justification
- Justification for data waiving:
- other:
- Justification for type of information:
- The study is ongoing and this information will be submitted later based on ECHA communication/decision number CCH-D-2114453640-54-01/F
Referenceopen allclose all
Description of key information
1. After the exposure of test chemical with fish for 28 days, NOEC was observed at 0.134 mg/l.
2. After the exposure of test chemical with fish for 28 days, NOEC was observed at 0.173 mg/l.
Thus on the basis of above available data, it can be concluded that the test chemical was toxic to fish and classified as aquatic chronic 3 as per the CLP classification criteria.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.134 mg/L
Additional information
Various long term studies available for the test chemical and structually and functionally similar read across chemicals were reviewed to determine the toxic nature of test chemical on the mortality and other long term effect of fish. The studies are as mentioned below:
Based on the prediction, the long term toxicity on fish was predicted for test substance. On the basis of no effects were observed in a freshwater system, the NOEC value for the test substance is estimated to be 0.134 mg/l for fish for 28 days of exposure duration. Based on this value, it can be concluded that the test chemical can be considered as toxic to fish at environmentally relevant concentrations and can be considered to be classified as aquatic chronic 3 category as per the CLP classification criteria.
Similarly in the another study based on the prediction, the long term toxicity on fish was predicted for test substance. On the basis of no effects observed in a freshwater system, the NOEC value for the test substance is estimated to be 0.173 mg/l for fish for 28 days of exposure duration. Based on this value, it can be concluded that the test chemical can be considered as toxic to fish at environmentally relevant concentrations and chemical was readily biodegradable in water thus on that basis it can be considered to be classified as aquatic chronic 3 category as per the CLP classification criteria.
Thus on the basis of above available data, it can be concluded that the test chemical was toxic to fish and classified as aquatic chronic 3 as per the CLP classification criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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