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EC number: 602-769-3 | CAS number: 122397-96-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- July - September 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Version / remarks:
- 17 July 2002
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- The Secondary effluent of the JRF Sewage Treatment Plan was used as inoculum. The Secondary effluent of a treatment plant was filtered through Whatman No. 1 filter paper, analysed for concentration and found 1.42 x 104 CFU/mL (Bacteria) and 3.00 x 102 CFU/mL (Fungus). Then inoculum was incubated at test temperature 22 +/- 2 °C for 7 days.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 2.1 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Potassium dihydrogen orthophosphate, Dipotassium hydrogen orthophosphate, Disodium hydrogen orthophosphate dihydrate, Ammonium chloride, Calcium chloride dihydrate, Magnesium sulphate heptahydrate, Iron (III) chloride hexahydrate
- Test temperature: 22 +/- 2 ºC
- pH:
TEST SYSTEM
- Culturing apparatus: BOD Incubator (Sky Lab Instruments & Engineering Pvt. Ltd.)
- Number of culture flasks/concentration: 10 bottles for test suspension, 10 bottles for inoculum blank, 10 bottles for procedure control and 6 bottles for toxicity control
- Method used to create aerobic conditions: The mineral medium was strongly aerated by using an aerator for 20 minutes and then allowed to stand for 20 h at 22 ± 2°C.
- Measuring equipment: Dissolved Oxygen Meter (HACH - USA)
SAMPLING
- Sampling method and frequency: Dissolved oxygen was measured with DO meter on day 7, 14, 21, and 28.
CONTROL AND BLANK SYSTEM
- Inoculum blank: The inoculum blank was prepared by mixing 4.0 mL inoculum with 3996.0 mL mineral medium.
- Toxicity control: The toxicity control was prepared by mixing 2.0 mL stock solution of potassium hydrogen phthalate, 2.0 mL stock solution of test item and 2.0 mL of inoculum to 1994 mL of mineral medium in a conical flask of 2 L capacity. The solution was mixed thoroughly. The final concentration was 2.00 mg/L of reference substance and 2.10 mg/L of test item in mineral medium.
- Reference substance:
- other: hydrogen phthalate
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 61.71
- Sampling time:
- 28 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 28.09
- Sampling time:
- 7 d
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Degradation of the test item reached 61.71% on 28 day of analysis, whereas the reference substance exhibited a normal pattern of degradation (up to 83.83%) within 28 days. Hence, the test item was readily biodegradable. The percent degradation in the toxicity control was more than 25% after 14 days. Therefore, the test item is assumingly not inhibitory to microbial activity in the inoculum.
- Executive summary:
Degradation of the test item reached 61.71% on 28 day of analysis, whereas the reference substance exhibited a normal pattern of degradation (up to 83.83%) within 28 days. Hence, the test item was readily biodegradable. The percent degradation in the toxicity control was more than 25% after 14 days. Therefore, the test item is assumingly not inhibitory to microbial activity in the inoculum.
Reference
Description of key information
Degradation of the test item reached 61.71% on 28 day and 28.09% after 7 days.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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