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EC number: 483-300-8 | CAS number: 99580-93-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2008-03-14 till 2008-03-21
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline-conform study under GLP without deviations.
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- Version / remarks:
- ; OECD 111 (2004)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Radiolabelling:
- no
- Analytical monitoring:
- yes
- Duration:
- 120 h
- pH:
- 4
- Temp.:
- 50 °C
- Initial conc. measured:
- 1 560 mg/L
- Duration:
- 120 h
- pH:
- 7
- Temp.:
- 50 °C
- Initial conc. measured:
- 1 560 mg/L
- Duration:
- 120 h
- pH:
- 9
- Temp.:
- 50 °C
- Initial conc. measured:
- 1 560 mg/L
- Number of replicates:
- Single replicate for each measuring date.
- Positive controls:
- no
- Negative controls:
- no
- Preliminary study:
- A preliminary test is performed at 50 ± 0.5°C at three pH values, 4.0 ; 7.0 and 9.0.
If this test indicates that 50% or more of the test article has been hydrolysed in 2.5 hours at 50°C, or less than 10% has been hydrolysed after five days at each of the three pH values (4.0 ; 7.0 and 9.0), no further testing is necessary. - Test performance:
- The experiment is carried out at 50 +/- 0.5°C. and several samples of each pH solution are analysed at different times in order to cover a suitable range of hydrolysis to test for pseudo-first order behaviour of the reaction.
From data obtained by this test, it is reliably possible to conclude if the hydrolysis reaction is pseudo-first order, then the test is repeated for each pH value either at one temperature lower than 40°C or at two temperatures above 50°C, differing from each other by at least 10°C. - Transformation products:
- no
- Details on hydrolysis and appearance of transformation product(s):
- The abiotic degradation hydrolysis for both cationic and anionic part of the test sample is lower than 10% after 5 days at 50°C for the three pH values (4.0, 7.0 and 9.0) tested. No transformation product(s) were analysed.
- % Recovery:
- ca. 99.9 - <= 100
- pH:
- 4
- Temp.:
- 50 °C
- Duration:
- 5 d
- Remarks on result:
- hydrolytically stable based on preliminary test
- % Recovery:
- ca. 99.9 - <= 100
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 5 d
- Remarks on result:
- hydrolytically stable based on preliminary test
- % Recovery:
- ca. 99.9 - <= 100
- pH:
- 9
- Temp.:
- 50 °C
- Duration:
- 5 d
- Remarks on result:
- hydrolytically stable based on preliminary test
- Key result
- pH:
- 4
- Temp.:
- 50 °C
- Type:
- not specified
- Remarks on result:
- hydrolytically stable based on preliminary test
- Key result
- pH:
- 7
- Temp.:
- 50 °C
- Type:
- not specified
- Remarks on result:
- hydrolytically stable based on preliminary test
- Key result
- pH:
- 9
- Temp.:
- 50 °C
- Type:
- not specified
- Remarks on result:
- hydrolytically stable based on preliminary test
- Details on results:
- No abiotic hydrolytic degradation observable.TEST CONDITIONS
- pH, sterility, temperature, and other experimental conditions maintained throughout the study: Yes
- Anomalies or problems encountered (if yes): no
MINOR TRANSFORMATION PRODUCTS
Maximum concentrations in % of the applied amount:
- at pH5, pH7, pH9: The abiotic degradation hydrolysis for both cationic and anionic part of the test sample is lower than 10 % after 5 days at 50 °C for the three pH values (4.0, 7.0 and 9.0) tested.
- Validity criteria fulfilled:
- yes
- Conclusions:
- From the experimental data obtained according to the guideline C.7 in Official Journal L 383 Part A, it can be concluded that the abiotic degradation hydrolysis for both cationic and anionic part of the test sample is lower than 10% after 5 days at 50°C for the three pH values (4.0, 7.0 and 9.0) tested.
Reference
Comments:
The abiotic degradation hydrolysis for both cationic and
anionic part of the test sample
is lower than 10 % after 5 days at 50 °C for the three pH
values (4.0, 7.0 and 9.0) tested.
Die Halbwertszeit t1/2 für den hydrolyt.Abbau beträgt > 8760 h (ph 7, 25 °C).
Description of key information
not hydrolytic degradable
Key value for chemical safety assessment
Additional information
The substance cannot be considered to be abiotic degradable. At three pH values tested (4.0, 7.0 and 9.0) the degradation rate was less than 10%.
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