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Diss Factsheets
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EC number: 278-947-6 | CAS number: 78560-45-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2015-12-03 to 2016-02-08
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- GLP compliance:
- no
- Other quality assurance:
- ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
- Type of method:
- differential scanning calorimetry
- Key result
- Melting / freezing pt.:
- -21 °C
- Atm. press.:
- 1 013 hPa
- Decomposition:
- no
- Conclusions:
- The melting temperature of the substance was determined to be -21°C at 1013 hPa using a relevant test method. The result is considered to be reliable.
Reference
Preliminary thermogravimetric measurement
A preliminary thermogravimetric measurement was performed over a temperature range from room temperature to ca. 600°C.
Beginning at room temperature the mass loss rate increased steadily, reaching a maximum at 150°C. At approximately 160°C the mass loss was practically complete, considering the initial mass loss from purging (ca. 0.5 %) before the start of the measurement. Until 600 °C there was no residue left (TGA curve attached).
DSC measurements
The DSC measurements were performed twice.
After cooling to -150°C at a rate of 2 K/min the sample was heated to 300°C at a rate of 5 K/min. The cooling curve exhibits a broad, not very sharp exothermic crystallisation peak with multiple maxima at around -45°C.
It is to be noted that crystallisation processes are often impaired by supercooling, due to a kinetic delay of the transformation caused by inhibited nucleation. Thus the measured transformation temperature does not necessarily correspond to the thermodynamic equilibrium temperature, but is strongly dependant on the thermal history of the sample and the applied cooling rate. Therefore cooling and heating cycle yield different enthalpy profiles.
The heat flow curve shows two sharp endothermic peaks. One with a peak maximum temperature at -19°C and an extrapolated onset temperature of -21°C, indicating the melting temperature (DSC curve attached).
Description of key information
Freezing point: -21°C (OECD 102)
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -21 °C
Additional information
A melting temperature value of -21°C at 1013 hPa was determined for the substance using a Differential Scanning Calorimetry (DSC) in accordance with OECD Test Guideline 102 and in compliance with a known quality system (ISO 17025). The result is considered to be reliable and is selected as key study.
In a secondary source to which reliability could not be assigned, melting temperature value of -32°C at 1013 hPa was reported for the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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