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EC number: 203-784-4 | CAS number: 110-62-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Test performed in 1998.
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: NITE: Data from reliable database OECD SIDS: Data from reliable peer-reviewed source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 15.9, 28.6, 51.4, 92.6, 166.7, and 300.0 mg/L
- Vehicle:
- yes
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: test substance dissolved in HCO-50
- Differential loading: Each test solution was prepared by adding the original test solution to dilution water.
- Controls: blank, vehicle control (100 mg/L HCO-50)
- Chemical name of vehicle (organic solvent, emulsifier or dispersant): dispersion adjuvant: hardened castor oil (HCO-50) - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Water flea
- Source: original source from National Institute for Environmental Studies; culture at test facility
- Age at study initiation (mean and range, SD): first instar (< 24 h)
- Feeding during test: none - Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 224 mg/L as CaCO3
- Test temperature:
- 19.6 to 19.9 °C
- pH:
- 7.0 to 7.6
- Dissolved oxygen:
- 7.9 to 8.9 mg/L (89 to 100% oxygen saturation)
- Nominal and measured concentrations:
- nominal: 15.9, 28.6, 51.4, 92.6, 166.7, and 300.0 mg/L
mean measured: <2.0, 4.7, 20.6, 48.2, 80.6, and 177.1 mg/L - Details on test conditions:
- TEST SYSTEM
- Test vessel:
- Type (delete if not applicable): open
- Material, size, headspace, fill volume: glass beaker, 100 mL test solution
- Aeration:
- Type of flow-through (e.g. peristaltic or proportional diluter):
- Renewal rate of test solution (frequency/flow rate):
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
- No. of vessels per vehicle control (replicates): 4
- Biomass loading rate: 1 animal/ 20 mL
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Elendt M4
OTHER TEST CONDITIONS
- Photoperiod: 16 h light : 8 h dark
- Light intentsity: 739 to 950 lux
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
- immobility: 24 h, 48 h
TEST CONCENTRATIONS
- Spacing factor for test concentrations: ca. 1.8 - Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 31.5 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- act. ingr.
- Basis for effect:
- mobility
- Remarks on result:
- other: 95% CL: 20.6 to 48.2 mg/L
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 20.6 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- act. ingr.
- Basis for effect:
- mobility
- Details on results:
- See IUCLID section "Any other information on results incl. tables"
- Validity criteria fulfilled:
- yes
- Conclusions:
- Daphnia magna: 48-h EC50 = 32 mg/L (NITE, 2010)
- Executive summary:
Valeraldehyde was tested on the aquatic invertebrate Daphnia magna in a immobilisation test following OECD 202. The test period was 48 hours. Test concentrations were analytically verified. The 48-hour EC50 was 32 mg/L (NITE, 2010).
Reference
Immobilization
Test item concentration (mg/L) |
Number of immobilized aninmals (percentage of total exposed) |
||
nominal |
mean measured1 |
24 hours |
48 hours |
Control |
<2.02 |
0 |
0 |
15.9 |
<2.02 |
0 |
0 |
28.6 |
4.7 |
0 |
0 |
51.4 |
20.6 |
0 |
0 |
92.6 |
48.2 |
16 (80) |
20 (100) |
166.7 |
80.6 |
20 (100) |
20 (100) |
300.0 |
177.1 |
20 (100) |
20 (100) |
1: Mean measured concentration = mean of 0-hour and 24-hour concentration values
2: analytical detection limit for valeraldehyde
Description of key information
Waterflea (D. magna): 48-h EC50 = 32 mg/L (OECD 202; NITE, 2010)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 32 mg/L
Additional information
The acute toxicity to aquatic invertebrates was determined in a 48-h acute toxicity test. The EC50 was 32 mg/L (measured).
Hence, valeraldehyde is acutely harmful to aquatic invertebrates.
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