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Diss Factsheets
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EC number: 218-076-0 | CAS number: 2049-95-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP Guideline Study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- Principles of method if other than guideline:
- One minor deviation from OECD Guideline 301 D is that ammonium chloride is omitted from the medium to prevent nitrification.
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: RWZI Horstermeer, Nederhorst den Berg, the Netherlands. This is an activated sludge plant treating
predominantly (>85%) domestic waste water.
- Pretreatment: The sludge was preconditioned to reduce the endogenous respiration rate. The diluted sludge (50 mg dry weight/litre) was aerated for a period of one week.
- Concentration of sludge: the sludge was diluted to a concentration of 2 mg dry weight/l in the test bottles.
- Water filtered: no. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 8.5 mg/L
- Based on:
- act. ingr.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Mineral salt solution prepared in distilled water.
- Solubilising agent (type and concentration if used): Not applicable.
- Test temperature: 20°C.
- pH: 7.0 (mineral salt solution), 7.1 (test solution)
- pH adjusted: no
- Continuous darkness: yes
TEST SYSTEM
- Culturing apparaturs: 280 ml BOD bottles
- Number of culture flasks/concentration: 10 bottles per treatment.
SAMPLING
- Sampling frequency: on Day 0, 7, 14, 21 and 58.
- Sampling method: the oxygen content was measured in the bottle.
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: no
- Toxicity control: yes - Reference substance:
- acetic acid, sodium salt
- Preliminary study:
- Not applicable.
- Parameter:
- % degradation (O2 consumption)
- Value:
- 3.9
- Sampling time:
- 28 d
- Details on results:
- Tertiary-amylbenzene was not toxic to the micro-organisms, because sodium acetate was degraded in the presence of tertiary-amylbenzene for
more than 25%. - Results with reference substance:
- The biodegradation of sodium acetate in the control series (group C) was used as a parameter for microbial activity of the inoculum. Within 14 days
86% of the sodium acetate was degraded. Therefore it can be concluded that the microbial activity of the inoculum was sufficient. - Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- Under the test conditions of this study, tertiary-amylbenzene is not considered as readily biodegradable.
- Executive summary:
The biodegradability of Tertiary-amylbenzene was determined following OECD guideline 301 D and according to GLP.
Tertiary-amylbenzene was added to an aqueous mineral salt medium and exposed to relatively low numbers of unadapted micro-organisms under aerobic conditions for a period of 28 days. The test compound was the only source of carbon and energy which was available to micro-organisms. To follow the biodegradation of tertiary-amylbenzene, the oxygen consumption by the micro-organisms was determined.
The reference compound sodium acetate was degraded for > 60% (86%) within 14 days. Therefore it can be concluded that the microbial activity of the inoculum was sufficient.
Sodium acetate was also degraded in the presence of tertiary-amylbenzene during the test period. This indicates that tertiary-amylbenzene is not toxic to the micro-organisms at the tested concentration of 2.0 mg/L.
Tertiary-amylbenzene was not sifnificantly degraded (<= 16% during the course of the study), therefore, the test substance is not considered as readily biodegradable according to EU criteria.
Reference
Description of key information
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.