Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 427-670-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 6 May 1998 - 4 June 1998
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study has been performed according to OECD and EC guidelines and in compliance with GLP principles.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 998
- Report date:
- 1998
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- yes
- Remarks:
- 1. total CO2 evolution in control vessels exceeds 40 mg/l medium (although below max allowed 70 mgl medium) 2. validity criterium IC/TC ratio < 5% not evaluated
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- Deviations:
- yes
- Remarks:
- see deviations OECD 301B
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EPA OPPTS 835.3110 (Ready Biodegradability)
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
Test material
- Details on test material:
- Description: yellow/green powder
Batch number: 6090
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- A mixed population of activated sewage sludge micro-organisms sampled from Severn Trent Water Plc sewage treatment plant at Belper, Derbyshire, UK (treats predominantely domestic sewage). Three times washed by settlement and resuspension in culture medium and maintained under continuous aeration.
- Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 16.1 mg/L
- Based on:
- test mat.
- Initial conc.:
- 10 other: mg C/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of culture medium: according to OECD 301
- Additional substrate: No
- Solubilising agent (type and concentration if used): None used
- Test temperature: 21 +/- 1°C
- pH: not reported
- pH adjusted: Not reported
- Aeration of dilution water: Yes
- Suspended solids concentration: 30 mg/L
- Continuous darkness: Yes
TEST SYSTEM
- Culturing apparatus: 5L vessels (3L medium)
- Number of culture flasks/concentration: 2/10 mg C/l
- Method used to create aerobic conditions: continuous magnetic stirring, continuous aeration with CO2 free air at a rate of approx 40 ml/minute
- Measuring equipment: TOC analyser
- Details of trap for CO2 and volatile organics if used: 2 traps (500 ml Dreschel bottles), 0.05 M NaOH
SAMPLING
- Sampling frequency:
CO2 traps: 0, 1, 2, 3 (not analysed), 5, 7, 9, 11 (not analysed), 13, 15, 17 (not analysed), 20, 22, 27, 28 and 29 days;
- Sample storage before analysis: None
CONTROL AND BLANK SYSTEM
- Inoculum blank (control): Yes, duplicate
- Reference (sodium benzoate): Yes, duplicate, 10 mg C/l
- Abiotic sterile control: No
- Toxicity control: Yes, single
STATISTICAL METHODS: not reported
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
- Preliminary study:
- not performed
- Test performance:
- CO2 evolution in control vessel was 55 mg/L after 28 days. This satisfies the OECD 301B validity criterion.
IC/TC ratio: see 'overall remarks'
Difference between replicates was <20%. This satisfies the OECD 301B validity criterion.
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 17
- Sampling time:
- 28 d
- Details on results:
- The total CO2 evolution in the control vessels on day 28 was 55 mg/l (= 201 mg/ 3 l). Although the CO2 evolution was in excess of 40 mg/l at the end of the test, this was considered not to affect the integrity of the study as the upper level of 70 mg/l given in the OECD guideline was not exceeded.
toxicity control: >25% after 14 days, 54% after 28 days
standard material: degradation > 60% by day 14 (80% after 15 days)
IC/TC ratio: not reported
pH of the test solutions: not reported
BOD5 / COD results
- Results with reference substance:
- Based on CO2 evolution:
Day 0: 0%
Day 1: 8%
Day 2: 32%
Day 3: 55%
Day 5: 64%
Day 7: 75%
Day 9: 75%
Day 13: 77%
Day 15: 80%
Day 20: 90%
Day 22: 92%
Day 27: 96%
Day 28: 92%
Day 29: 89%
Any other information on results incl. tables
Theoretical carbon content of the test material was calculated to be 61.99%.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
- Conclusions:
- Under the conditions of the CO2 evolution test was the test material shown to be not readily biodegradable (17% degradation after 28 days).
- Executive summary:
The ready biodegradability of the test material was assessed according to OECD 301B CO2 evolution test (Modified Sturm Test). The test was performed in agreement with the OECD 301B guideline and fulfilled the validity criteria. No biodegradation of the test material was observed (based on CO2 evolution). The test substance is therefore not ready biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Although ECHA is providing a lot of online material in your language, part of this page is only in English. More about ECHA’s multilingual practice.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
the-echa-website-uses-cookies
find-out-more-on how-we-use-cookies