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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

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Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Qualifier:
no guideline available
Principles of method if other than guideline:
Materials and methods are well-described in the publication.
GLP compliance:
no
Analytical monitoring:
no
Details on test solutions:
For the main test neutralized solutions were used. A test without neutralization was performed as well.
Test organisms (species):
Daphnia magna
Details on test organisms:
Daphnia magna, strain: IRCHA
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
24 h
Test temperature:
20 °C
pH:
8.0 ± 0.2
Dissolved oxygen:
>= 2 mg/L
Key result
Duration:
24 h
Dose descriptor:
EC50
Remarks:
neutralized
Effect conc.:
1 535 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Key result
Duration:
24 h
Dose descriptor:
EC0
Remarks:
neutralized
Effect conc.:
1 206 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Key result
Duration:
24 h
Dose descriptor:
EC100
Remarks:
neutralized
Effect conc.:
2 083 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
24 h
Dose descriptor:
EC50
Remarks:
non-neutralized
Effect conc.:
85 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: mortality caused by acidity
Duration:
24 h
Dose descriptor:
EC0
Remarks:
non-neutralized
Effect conc.:
73 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other:
Remarks:
mortality caused by acidity
Duration:
24 h
Dose descriptor:
EC100
Remarks:
non-neutralized
Effect conc.:
98 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other:
Remarks:
mortality caused by acidity
Validity criteria fulfilled:
not specified
Conclusions:
In neutralized solutions, an EC50 of 1535 mg/L, an EC0 of 1206 mg/L and an EC100 of 2083 mg/L, respectively, can be stated.
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Justification for type of information:
Potassium citrate salts are known to show a very high solubility in water and dissociate rapidly.
Potassium in known to be non-toxic. The toxicity is determined by the citrate moiety of the substance.
Because of that a read-across to citric acid is suitable for the determination of the toxicity.
Reason / purpose for cross-reference:
read-across source
Qualifier:
no guideline available
Principles of method if other than guideline:
Materials and methods are well-described in the publication.
GLP compliance:
no
Analytical monitoring:
no
Details on test solutions:
For the main test neutralized solutions were used. A test without neutralization was performed as well.
Test organisms (species):
Daphnia magna
Details on test organisms:
Daphnia magna, strain: IRCHA
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
24 h
Test temperature:
20 °C
pH:
8.0 ± 0.2
Dissolved oxygen:
>= 2 mg/L
Key result
Duration:
24 h
Dose descriptor:
EC50
Remarks:
neutralized
Effect conc.:
1 535 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Key result
Duration:
24 h
Dose descriptor:
EC0
Remarks:
neutralized
Effect conc.:
1 206 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Key result
Duration:
24 h
Dose descriptor:
EC100
Remarks:
neutralized
Effect conc.:
2 083 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
24 h
Dose descriptor:
EC50
Remarks:
non-neutralized
Effect conc.:
85 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: mortality caused by acidity
Duration:
24 h
Dose descriptor:
EC0
Remarks:
non-neutralized
Effect conc.:
73 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other:
Remarks:
mortality caused by acidity
Duration:
24 h
Dose descriptor:
EC100
Remarks:
non-neutralized
Effect conc.:
98 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other:
Remarks:
mortality caused by acidity
Validity criteria fulfilled:
not specified
Conclusions:
In neutralized solutions, an EC50 of 1535 mg/L, an EC0 of 1206 mg/L and an EC100 of 2083 mg/L, respectively, can be stated.

Description of key information

In neutralized solutions, an EC50 of 1535 mg/L, an EC0 of 1206 mg/L and an EC100 of 2083 mg/L, respectively, can be stated.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
1 535 mg/L

Additional information