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EC number: 604-012-2 | CAS number: 137296-15-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- November, 1941
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Lactic acid had been prepared by the method of Smith and Claborn and an analysis (by a modified Eder and Kutter procedure) gave 60 % “directly titratable acid” and 102.0 % “total acid”, both expressed as lactic acid. It had the following physical properties: refractive index = 1.4361 (25 °C) and relative density = 1.2143 (25 °C).
The saturated Ammonium lactate solution was prepared by passing dry ammonia into lactic acid diluted with about 10 % water. The ammonia was passed in under reflux, until the theoretical amount had been absorbed. At first an odor of ammonia persisted, but this disappeared after the solution had stood in a glass-stoppered bottle for one week. The ammonia content of the solution was determined by Kjeldahl distillation. - GLP compliance:
- no
- Type of method:
- other: Ammonia content determined by Kjeldahl distillation.
- Key result
- Water solubility:
- 1 077 g/L
- Conc. based on:
- test mat. (dissolved fraction)
- Remarks on result:
- other: Temperature and pH not reported in the literature.
- Details on results:
- The maximum achievable concentration of Ammonium lactate in water is approximately 90 % (w/w). The water solubility of the substance is reported to be approximately 1077 g/L.
- Conclusions:
- For determination of the physical-chemical properties of differently concentrated Ammonium lactate solutions, an aqueous stock solution was prepared by passing dry ammonia into lactic acid containing approximately 10 % water. The ammonia was passed in under reflux, until the theoretical amount had been absorbed. At first an odour of ammonia persisted, but this disappeared after the solution had stood in a glass-stoppered bottle for one week. The ammonia content of the solution was determined by Kjeldahl distillation. The maximum achievable concentration of Ammonium lactate in water is approximately 90 % (w/w). The water solubility of the substance is reported to be approximately 1077 g/L.
- Executive summary:
For determination of the physical-chemical properties of different concentrated Ammonium lactate solutions, an aqueous stock solution was prepared by passing dry ammonia into lactic acid containing approximately 10 % water. The ammonia was passed in under reflux, until the theoretical amount had been absorbed. At first an odor of ammonia persisted, but this disappeared after the solution had stood in a glass-stoppered bottle for one week. The ammonia content of the solution was determined by Kjeldahl distillation. The maximum achievable concentration of Ammonium lactate in water is approximately 90 % (w/w). The water solubility of the substance is reported to be approximately 1077 g/L.
- Endpoint:
- water solubility
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- For details and justification of read-across please refer to the report attached in section 13 of IUCLID.
- Reason / purpose for cross-reference:
- read-across source
- Key result
- Water solubility:
- 1 077 g/L
- Conc. based on:
- test mat. (dissolved fraction)
- Remarks on result:
- other: Temperature and pH not reported in the literature.
- Conclusions:
- The water solubility of Ammonium-(S)-lactate is derived by read-across to Ammonium lactate. The chirality of the test item Ammonium lactate used in the experimental study performed by Dietz et al. (1941) was not specifed. However, it is assumed that chirality has only a minor influence on water solubility. Thus, the water solubility of Ammonium-(S)-lactate can also be given as 1077 g/L.
- Executive summary:
For determination of the physical-chemical properties of differently concentrated Ammonium lactate solutions, an aqueous stock solution was prepared by passing dry ammonia into lactic acid containing approximately about 10 % water. The ammonia was passed in under reflux, until the theoretical amount had been absorbed. At first an odor of ammonia persisted, but this disappeared after the solution had stood in a glass-stoppered bottle for one week. The ammonia content of the solution was determined by Kjeldahl distillation. The maximum achievable concentration of Ammonium lactate in water is approximately 90 % (w/w). The water solubility of the substance is reported to be approximately 1077 g/L.
This information is used in a read-across approach in the assessment of the target substance. For justification of read-across please refer to the attached read-across report (see IUCLID section 13).
Referenceopen allclose all
Description of key information
For determination of the physical-chemical properties of differently concentrated Ammonium lactate solutions, an aqueous stock solution was prepared by passing dry ammonia into lactic acid containing approximately 10 % water. The ammonia was passed in under reflux, until the theoretical amount had been absorbed. At first an odour of ammonia persisted, but this disappeared after the solution had stood in a glass-stoppered bottle for one week. The ammonia content of the solution was determined by Kjeldahl distillation. The maximum achievable concentration of Ammonium lactate in water is approximately 90 % (w/w). The water solubility of the substance is reported to be approximately 1077 g/L.
Key value for chemical safety assessment
- Water solubility:
- 1 077 g/L
- at the temperature of:
- 20 °C
Additional information
This information is used in a read-across approach in the assessment of the substance to be registered. For details and justification of read-across please refer to the report attached in section 13 of IUCLID.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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