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EC number: 310-231-1 | CAS number: 140203-21-0 The distillate from the fractional distillation of high-temperature coal tar having an approximate distillation range of 280°C to 450°C (536°F to 842°F). Composed primarily of tri- and polynuclear aromatic hydrocarbons.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Principles of method if other than guideline:
- As a summation parameter, TOC was measured rather than single PAHs.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Specific details on test material used for the study:
- - Physical state: solid (here: applied as fine-granular powder < 180 µm)
- Density: 1.30 – 1.35 g/cm³ (20°C) (DIN 51 757)
- Stability under test conditions: WSF (water-soluble fraction): limited
- Storage condition of test material: room temperature, exclusion of light - Key result
- Water solubility:
- 0.242 mg/L
- Conc. based on:
- other: dissolved organic carbon (DOC)
- Loading of aqueous phase:
- 1 000 mg/L
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- 6.8
- Remarks on result:
- other: average over 3 time intervals (24, 48, and 72 h) measured in replicate samples
- Water solubility:
- 0.215 mg/L
- Conc. based on:
- other: dissolved organic carbon (DOC)
- Loading of aqueous phase:
- 100 mg/L
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- pH:
- 6.7
- Remarks on result:
- other: average at 72 h (replicate samples)
- Endpoint:
- water solubility
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
1. HYPOTHESIS FOR THE ANALOGUE APPROACH
The target compound, Distillates (coal tar), high-temperature, heavy oils (EC no. 310-231-1; CAS no. 140203-21-0) as well as the read-across (source) compound, pitch (coal tar) [CAS No. 65996-93-2] are coal tar-borne UVCB substances consisting of a complex mixture of polycyclic aromatic hydrocarbons (PAH), predominantly of condensed four to five-ring aromatic ring systems which form a matrix that is practically insoluble in water. The GC-analytical profiles are very similar, and hence will be the physico-chemical and toxicological properties of these structure-related fractions. It is expected that the mammalian systemic and local or environmental toxicity of the target compound will not be higher than that of the read-across compound, pitch (coal tar).
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
The read-across (source) compound, pitch (coal tar), as heavy coal-tar distillate, shows a very similar PAH-profile: This is due to the fact that the considered coal-tar pitch is the high-molecular, "heavy" RESIDUE of a sequential fractionation procedure of coal tar with the temperature increasing, among others under vacuum distillation. On the other hand, the target compound is the high-termperature re-distillate of a high-molecular, heat-treated coal-tar fraction. This is expressed also in the respective fractions of total analysable GC-volatiles which amount to approx. 10% in coal-tar pich, while the GC volatiles of the target compound sum up to a comparable percentage of 13%.
3. ANALOGUE APPROACH JUSTIFICATION
By far the major part of the highly condensed matrix of Distillates (coal tar), high-temperature, heavy oils (EC no. 310-231-1; CAS no. 140203-21-0) is supposed to be biologically unavailable, as is pitch (coal tar ), the read-across source. This means, poor water solubility as well as mammalian and aquatic toxicological profiles are supposed to closely overlap. - Reason / purpose for cross-reference:
- read-across source
- Principles of method if other than guideline:
- Read-across to preceding entry:
Source test material: Pitch (coal tar), high temperature [CAS no. 65996-93-2]
Reference: RÜTGERS 1999a,b - Key result
- Water solubility:
- 0.037 mg/L
- Conc. based on:
- test mat. (dissolved fraction)
- Remarks:
- sum of 16 EPA PAH
- Loading of aqueous phase:
- 10 other: g percolated in a column by 1.1 L of water
- Incubation duration:
- 39 wk
- Temp.:
- 22 °C
- pH:
- 7
- Remarks on result:
- other: total cumulative eluted amount of EPA PAH with weekly renewal of 1 L elution medium
Referenceopen allclose all
Solubility Results for Pitch, coal tar, high temp(coal-tar pitch)
(Mean values of two replicates per time interval) (data taken from Table 4 of the report, modified)
Sample |
Carbon content [mg/L] |
|
||||
Dilution water1) |
0.732 |
Mean |
Mean over time (24, 48, 72 h)4) |
Mean over time (48, 72 h)4) |
Deviation (48, 72 h) [%] |
|
1000 mg/L |
No. 1 (24 h) |
0.320 |
0.2892) |
0.242 |
||
No. 2 (24 h) |
0.258 |
|||||
No. 1 (48 h) |
0.988 |
0.2043) |
0.218 |
14.5 |
||
No. 2 (48 h) |
0.883 |
|||||
No. 1 (72 h) |
0.930 |
0.2333) |
||||
No. 2 (72 h) |
1.000 |
|||||
100 mg/L |
No. 1 (72 h) |
0.186 |
0.2152) |
|
||
No. 2 (72 h) |
0.243 |
1) Dilution water for samples 48, 72 h at 1000 mg/L loading (measured 2010-11-15)
2) Mean values of replicates, dilution water carbon content not subtracted as dilution water carbon content
was 0 mg/L (measured 2010-11-12)
3) Mean values of replicates, dilution water carbon content subtracted (measured 2010-11-15)
4) The time average over 24,48, and 72 h was calculated, thus deviating from the study report in which only the average over 48 and 72 h has been quoted.
Description of key information
At loadings of 1000 and 100 mg pitch/L, the mean DOC of the water-soluble fraction (WAF) were 0.242 and 0.215 mg/L at 20 °C, respectively. A total of 37 µg (sum of 16 EPA PAH, cumulated after 39 wks) was found in the water extract after 39-fold repetitive weekly elutions of 10 g coal-tar pitch through a percolation column at 22 °C. The water solubilty of the target compound, Distillates (coal tar), high-temperature, heavy oils (EC no. 310-231-1; CAS no. 140203-21-0), is expected to be similar, i.e. in the range of >0.1 mg/L and << 1 mg/L, measured as DOC (see NOACK 2011).
Key value for chemical safety assessment
- Water solubility:
- 0.215 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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