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Diss Factsheets
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EC number: 232-001-9 | CAS number: 7783-49-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Remarks:
- dustiness
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- DIN 55992-1 (Determination of a parameter for the dust formation of pigments and extenders - Part 1: Rotation method)
- Deviations:
- yes
- Remarks:
- a seven stage cascade impactor is connected to a heubach dust meter
- Principles of method if other than guideline:
- The Heubach dust meter is modified in a way that a seven stage cascade impactor is connected to the system. This involves an additional air fed of 20 L/min via the coarse dust separator needed to supply the cascade impactor with 40 L/min air current as specified in the manufacturer’s specifications.
The calculation report: EBRC (2018)
The Multiple-Path Particle Dosimetry Model (MPPD, v2.1; CIIT, 2009) was used to predict this fractional deposition behaviour for workers.
The model algorithms calculate the deposition (and clearance) of mono-disperse and poly-disperse aerosols in the respiratory tract for particles ranging from ultra-fine (0.01 microns) to coarse (20 microns) sizes. Within each airway, the deposition is calculated using theoretically derived efficiencies for deposition by diffusion, sedimentation and impaction within the airway or airway bifurcation. Filtration of aerosols by the head is determined using empirical efficiency functions. - GLP compliance:
- no
- Type of method:
- rotating drum method
- Remarks:
- connected to a seven stage cascade impactor
- Type of distribution:
- volumetric distribution
- Mass median aerodynamic diameter:
- 27.18 µm
- Geometric standard deviation:
- 1.64
- Percentile:
- D50
- Remarks on result:
- not measured/tested
- Remarks on result:
- not measured/tested
- Conclusions:
- Total Dustiness (airborne fraction): 103.85 mg/g (DMT)
Mass median aerodynamic diameters (monomodal distribution) of airborne fraction: MMAD = 27.18 µm.
Geometric standard deviation: GSD = 1.64
Fractional deposition in human respiratory tract (MPPD model, based on calculated MMAD):
Head (ET): 50.42 %
Tracheobronchial (TB): 0.09 %
Pulmonary (PU): 0.03 % - Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2018-01-17
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- Version / remarks:
- 1981
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Version / remarks:
- 2009
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187
- Version / remarks:
- 2009
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- signed, 2017-02-28
- Type of method:
- Laser scattering/diffraction
- Type of distribution:
- volumetric distribution
- Remarks on result:
- not measured/tested
- Percentile:
- D10
- Mean:
- 0.7 µm
- St. dev.:
- 0
- Percentile:
- D50
- Mean:
- 3.7 µm
- St. dev.:
- 0
- Percentile:
- D90
- Mean:
- 76.9 µm
- St. dev.:
- 1.27
- Conclusions:
- According to OECD 110 (1981), ISO 13320 (2009) and CIPAC MT 187 (2009), strontium fluoride has following particle size distribution:
D10: 0.7 µm
D50: 3.7 µm (Median diameter)
D90: 76.9 µm
Referenceopen allclose all
Dustiness (airborne fraction): total: 103.85 mg/g.
In the original study report by DMT, the mass median diameter was not calculated. Since the deposited fractions were provided for each of the cascade impactor stages, it was possible to fit a monomodal lognormal distribution to the data by standard non-linear regression procedure. The MMAD and GSD were calculated as follows: MMAD = 27.18 µm, GSD = 1.64
As the cascade impactor already takes aerodynamic characteristics of the particles into account, the reported mass median diameter can be interpreted as the mass median aerodynamic diameter.
These data and the corresponding GSD were used as distribution parameters for the MPPD model enabling an estimation of deposited dust fractions in the human respiratory tract: These fractions were estimated as follows:
Head (ET): 50.42 %
Tracheobronchial (TB): 0.09 %
Pulmonary (PU): 0.03 %
Two test series of 3 measurements each were performed with the test item.
Test series 1 |
Test series 2 |
Average |
|
D10 |
0.7 µm |
0.7 µm |
0.7 µm |
D50 (Median diameter) |
3.7µm |
3.7 µm | 3.7 µm |
D90 | 77.8 µm | 76.0 µm | 76.9 µm |
The test item zinc fluoride as a median particle size D50 = 4 µm, which was determined by laser diffraction measurement in accordance to inter alia ISO 13320 (2009) and CIPAC MT 187 (2009) method.
Description of key information
Particle size distribution
D10: 0.7 µm
D50: 3.7 µm (Median diameter)
D90: 76.9 µm
Dustiness
Total Dustiness (airborne fraction): 103.85 mg/g (DMT)
MMAD = 27.18 µm.
GSD = 1.64
Fractional deposition in human respiratory tract (MPPD model, based on calculated MMAD)
Head (ET): 50.42 %
Tracheobronchial (TB): 0.09 %
Pulmonary (PU): 0.03 %
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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