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Physical & Chemical properties

Vapour pressure

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
05 October 2017 to 08 November 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: isothermal thermogravimetry
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
< 0 Pa
Key result
Test no.:
#2
Temp.:
20 °C
Vapour pressure:
< 0 mm Hg
Key result
Test no.:
#3
Temp.:
25 °C
Vapour pressure:
< 0 Pa
Key result
Test no.:
#4
Temp.:
25 °C
Vapour pressure:
< 0 mm Hg

In the range of 200°C and 230°C a log p versus 1/T curve for the test item could not be determined since an increase in weight was observed during the first experiment (data is archived in the raw data).

Since no accurate vapour pressure could be calculated from the obtained results, the weight losses were compared with the results of benzo(ghi)perylene. Since the weight loss of the test item was lower than the weight loss of the reference compound the vapour pressure of the test item is considered to be below the vapour pressure of benzo(ghi)perylene. According to this the vapour pressure of the test item is given below:

Vapour pressure of the Test Item

 

20°C

25°C

 

[Pa]

[mm Hg]

[Pa]

[mm Hg]

Test item

< 1.3E-8

< 1.0E-10

< 7.2E-8

< 5.4E-10

Conclusions:
The isothermal TGA effusion method was applied for the determination of the vapour pressure of 1,4 piperazinediethanesulfonic acid disodium salt.
The vapour pressure of the test item at 20°C (293K) was <1.3E-8 Pa and < 1.0E-10 mmHg and at 25°C (298K) was < 7.2E-8 and < 5.4E-10 mmHg.

Description of key information

The isothermal TGA effusion method was applied for the determination of the vapour pressure of 1,4 piperazinediethanesulfonic acid disodium salt.

The vapour pressure of the test item at 20°C (293K) was <1.3E-8 Pa and < 1.0E-10 mmHg and at 25°C (298K) was < 7.2E-8 and < 5.4E-10 mmHg.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
20 °C

Additional information