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Diss Factsheets
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EC number: 822-536-1 | CAS number: 2180952-76-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- According to QSAR estimation methods for various representative structures of C.I. Solvent Red (i.e. varying by 1-6 twelve carbon alkyl chain side groups) the water solubility ranged anywhere from 9.43E-13 to 6.52E-44 mg/L at 25 °C (WSKOW v1.42). Using the flask method, the water solubility of C.I. Solvent Red 175 was empirically determined to be less than 1.0E-4 g/L at 20°C. Using the HPLC method, the log (base 10) n-octanol/water partition coefficient (i.e. Log Kow) was determined to be > 6.5. The Log Kow estimates for the evaluated representative structures of C.I. Solvent Red 175 according to KOWWIN (v. 1.43) ranged from 15.17 to 44.92. The water solubility and Log Kow information clearly indicate that C.I. Solvent Red 175 is highly water insoluble.
The most water soluble structure of C.I. Solvent Red 175 (i.e. a single twelve carbon alkyl chain side group with smiles code = CCCCCCCCCCCCc1cc2c3c(ccc4c3c1c5ccc6c7c5c4ccc7c8ccccc8C6(=O))C(=O)c9c2)was evaluated for toxicity to green algae using the ECOSAR program (developed by the US Environmental Protection Agency’s Office of Chemical Safety and Pollution Prevention, v 1.11). The predicted EC50 for green algae was ~ 175,000x greater than the estimated water solubility limit. Furthermore, the predicted chronic value for green algae was ~688,000x greater than the estimated water solubility limit. Therefore, no toxic effects are predicted for the test material at water saturation, and an aquatic algal study is scientifically not necessary.
Reference
Description of key information
Neither acute nor chronic effects at water saturation were predicted for the test material, therefore acute and chronic testing with aquatic algae is waived since the study is scientifically not necessary.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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