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EC number: 225-245-2 | CAS number: 4736-60-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2003-12-11 to 2004-01-29
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- Adopted July 27,1995
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- December 1992
- GLP compliance:
- yes
- Type of method:
- flask method
- Key result
- Water solubility:
- 7.84 g/L
- Conc. based on:
- act. ingr. (total fraction)
- Temp.:
- 20.1 °C
- pH:
- 7.8
- Details on results:
- Preliminary test:
Test substance was stirred overnight with double distilled water at 20.3 ±0.5°C (nominal concentration was 19.0 g/L). The concentration of Ethyltriphenylphosphonium iodide in the aqueous phase after two and three successive times of centrifugation (3500 g, 5 min, 20°C) was 8.14 g/L and 7.84 g/L, respectively. From this it could be safely concluded that the water solubility of Ethyltriphenylphosphonium iodide is >/= 10 mg/L. Therefore, the flask method was chosen for the determination of the water solubility of Ethyltriphenylphosphonium iodide. The pH of the aqueous phase after two and three centrifugation steps was 7.4 and 6.9, respectively. Because no significant difference was observed between the concentrations analysed after the second and third centrifugation steps, it was concluded that all undissolved test substance had been removed after two centrifugation steps. Therefore, it was decided to centrifuge the water samples from the main study twice.
Main study (flask method):
Test substance was stirred with double distilled water (in triplicate) at a nominal concentration of approximately 42 g/L. Duplicate samples were taken from each water mixture after 24, 48 or 72 hours of stirring. Undissolved test substance was removed by two successive centrifugation steps (3500 g, 5 min, 20°C). The aqueous phases were analysed for Ethyltriphenylphosphonium iodide. The temperature of the climate room was 20.1 ±0.9°C during the performance of the test.
One of the 72 hours stirred water sample was also centrifuged a third time. Because no significant difference was observed between the concentrations analysed after the second centrifugation step (7.83 g/L) and third centrifugation step (7.89 g/L), it was concluded that all undissolved test substance had been removed after two centrifugation steps.
The duplicate samples of the 24-hour measurement deviated by 20% from each other. Therefore, the water solubility of Ethyltriphenylphosphonium iodide was calculated as the mean value of the 48- and 72- hour measurements.
The water solubility of Ethyltriphenylphosphonium iodide at 20.1 ±0.9°C was determined to be 7.84 g/L using the flask method. The pH of the aqueous sample after 72 hours stirring was 7.8. - Conclusions:
- The water solubility of Ethyltriphenylphosphonium iodide was determined to be 7.84 g/L at 20.1 ± 0.9°C by using the flask method. The pH of the aqueous sample after 72 hours stirring was 7.8.
Reference
Description of key information
7.84 g/L at 20.1 ± 0.9°C
The pH of the aqueous sample after 72 hours stirring was 7.8.
Key value for chemical safety assessment
- Water solubility:
- 7.84 g/L
- at the temperature of:
- 20.1 °C
Additional information
GLP study according to OECD Guideline 105 (adopted 27 July 1995) and EU method A.6 (December, 1992) using the flask method
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