Registration Dossier
Registration Dossier
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EC number: 275-148-4 | CAS number: 71033-19-7
Endpoint summary
Administrative data
Description of key information
EC50 (48h) invertebrate Daphnia: 54.9 mg/L
EC50 (7d) aquatic plants Lemna minor: > 91.0 mg/L (frond number, dry weight)
NOEC (7d) aquatic plants Lemna minor: 4.27 mg/L (frond number, dry weight)
Additional information
Invertebrate acute toxicity
The median effect concentration (EC50) and the no-effect concentration (NOEC) of the substance to Daphnia magna were investigated under static exposure conditions over a period of 48 h, following the guideline OECD 202 and EU C.2.
The investigated nominal concentrations were 130, 59.1, 26.9, 12.2 and 5.55 mg/L test item, corresponding to 100, 45.5, 20.7, 9.39 and 4.27 mg/L of the active ingredient.
The EC50 Daphnia magna at 24h was found to be > 100mg/L, the EC50 Daphnia magna at 48h was found to be 54.9 mg/L based on based on the nominal concentrations of the active ingredient.
Aquatic Plants toxicity
The inhibitory effects of the substance to the duckweed Lemna minor were investigated over a period of 7 days, based on the frond number and biomass (dry weight), following the guideline OECD 221 and the EU C.26.
The test solutions were prepared by respective dilutions of a stock solution in STEINBERG medium. The test was performed at the nominal test item concentrations of 130, 50.0, 19.2, 7.40 and 2.84 mg/L, corresponding to 100, 38.5, 14.8, 5.69 and 2.19 mg/L of the active ingredient.
These analyses confirmed the right dosage of the test item, but showed that the concentrations of the test item decreased over the whole 7 day test period (91, 86, 61, 76 and 61%, respectively, of the initial value). Therefore, the effective concentrations (ErC50 and EyC50) were assessed based on the geometric mean (GM) of the measured concentrations of the active ingredient.
The NOEC frond number, on was found 4.27 mg/L of active ingredient.
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