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EC number: 270-099-5 | CAS number: 68411-06-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic plants other than algae
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic plants other than algae
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study with analytical monitoring.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 221 (Lemna sp. Growth Inhibition Test)
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Details on sampling:
- The frond numbers were determined on day 3, 5 and 7. The dry weight of each replicate from test end was determined at test termination.
- Vehicle:
- no
- Details on test solutions:
- PREPARATION OF TEST SOLUTION
The test item is not easily soluble in test water. To avoid physical effects of undissolved test item, no concentrations above the solubility limit of the test item in test water were tested.
Therefore, suspensions of the test item were prepared separately by suspending test item in test water at loading rates of nominal 10, 3.16, 1.0, 0.317 and 0.1 mg test item/L. These suspensions were stirred for 24 hours to dissolve as much test item as possible. Then, the undissolved test item was separated by filtration with a cellulose acetate filter (0.45 µm). The resulting filtrates are the Water Soluble Fractions which served as test solutions. The test solutions were prepared just before introduction of the aquatic plants (= start of the test).
In the control, test medium was used without addition of the test item. - Test organisms (species):
- Lemna gibba
- Details on test organisms:
- - Test organism: aquatic freshwater plant Lemna gibba G3
- The plants are cultured in the laboratories of ibacon under standardised conditions according to the test guidelines.
- The fronds introduced in the test were taken from ibacon's in-house laboratory culture.
CULTURING MEDIUM
- The 20XAAP medium recommended by OECD Guideline 221 was used as culturing medium as well as solvent for the test item.
- The pH was adjusted with 2 M HCl to 7.4. The test water was prepared 1 day before test start to allow pH to stabilise. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 7 d
- Hardness:
- 3.55 mmol/L as Carbon hardness
- Test temperature:
- 22 – 24°C
- pH:
- pH values at test start 7.5 to 7.8, at the end of the test 8.9 to 9.0;
- Nominal and measured concentrations:
- - Concentrations tested (nominal): Water soluble fractions (WSF), separately prepared from nominal loadings of 10, 3.16, 1.0, 0.317 and 0.1 mg test item/L and a control.
- The total organic carbon content was determined in all of the duplicate test media samples and in the duplicate control samples from both sampling times (0 hour and seven days). The measured values were uniform over time, ranging from 5 to 10 mg carbon/L (test media) and 5 to 8 mg carbon/L (control).
In view of the limited informative value of the TOC results, all reported effect data are based on nominal loading rates of the test item. - Details on test conditions:
- TEST SYSTEM
- Replicates per treatment: 3
- Replicates per control: 3
- Glass vessels of 250 mL volume with approximately 200 mL test medium, covered with glass dishes.
FURTHER TEST CONDITIONS
- continious illumination with 8283 Lux (mean value) with a range of 7940 to 8520 lux. - Reference substance (positive control):
- yes
- Remarks:
- 3,5 dichlorophenol
- Duration:
- 7 d
- Dose descriptor:
- EC10
- Effect conc.:
- > 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 7 d
- Dose descriptor:
- EC10
- Effect conc.:
- > 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 7 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 7 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Results with reference substance (positive control):
- ErC50 = 7.68 mg/L (frond number)
ErC50 = 7.1 mg/L (dry weight) - Validity criteria fulfilled:
- yes
- Endpoint:
- toxicity to aquatic plants other than algae
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to attached justification.
- Reason / purpose for cross-reference:
- read-across source
- Duration:
- 7 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 7 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
Referenceopen allclose all
Description of key information
With high probability acutely not harmful to aquatic plants
Key value for chemical safety assessment
Additional information
There are no studies available that assess the chronic toxicity of the test substance to aquatic plants. However, as the test substance belongs to the substance group of Phthalocyanines whose group members resemble in their chemical structure as well as in their phys-chem properties, a read-across approach was used to cover this endpoint.
The acute toxicity of Phthalocyanines to Lemna gibba was investigated by a test on CAS 59160-79-1 according to OECD 221. The study was conducted according to GLP and the exposure lastet 7 days. Acute toxicity (frond number) resulted in EC50 > 10 mg/L [Ibacon 2015].
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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