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Diss Factsheets
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EC number: 806-984-5 | CAS number: 1392411-89-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- not specified
- Type of method:
- flask method
- Key result
- Water solubility:
- > 38.1 - < 183.5 mg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 500 mg/L
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- pH:
- ca. 6 - ca. 7
- Conclusions:
- Under the study conditions, water solubility of the substance was estimated to be 31.8 – 183.5 mg/L at 20.0 ± 0.5°C, corresponding to 18.2 - 31.8% of the nominal concentration.
- Executive summary:
A study was conducted to determine the solubility of the substance according to OECD 105 and EU Method A.6. The solubility of the test substance in water was determined by measurement of DOC concentration (dissolved organic carbon) in the filtered test solutions using a TOC analyser. As solubility was dependent on nominal concentration, no exact value for the solubility of the test substance in water could be stated. Under the study conditions, water solubility of the substance was estimated to be 31.8– 183.5 mg/L at 20.0 ± 0.5°C, corresponding to 18.2 - 31.8% of the nominal concentration (Johannes, 2016).
Reference
The measurements from the flasks 1A-C (Days 5-7) (mean value) and 2-6 were included in the calculation of the solubility of the test substance in water.
Table 1: Measurements used for Calculation of Solubility:
Flask | Measured Conc. Test Sub. [mg/L] |
Nominal Conc. Test Sub.[mg/L] |
Dissolved Part [%] |
pH value |
2 | 17.8 | 100 | 31.78 | 6.41 |
3 | 45.9 | 302 | 27.15 | 6.49 |
Mean 1A-C | 67.3 | 503 | 23.90 | 6 -7 |
4 | 75.6 | 600 | 22.51 | 6.40 |
5 | 90.4 | 800 | 20.19 | 6.60 |
6 | 102.7 | 1009 | 18.18 | 6.63 |
As solubility was dependent on nominal concentration, no exact value for the solubility of the test substance in water can be stated. Therefore, the water solubility for the test substance lays in the range: 31.8 – 183.5 mg/L at 20.0 ± 0.5°C for the following nominal concentration range of the test substance in water: 100 – 1009 mg/L. Therefore, 18.2 – 31.8% of the nominal concentration of the test substance was dissolved. As dissolved carbon was measured as sum parameter for dissolved test substance, this study could not distinguish between water solubility and hydrolysis of the test substance.
Description of key information
The water solubility was determined according to OECD Guideline 105 and EU Method A.6 (Johannes, 2016).
Key value for chemical safety assessment
- Water solubility:
- 183.5 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.