Registration Dossier
Registration Dossier
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EC number: 700-169-7 | CAS number: 7646-67-5
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12 April 2007 and 21 September 2007
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- soil
- Radiolabelling:
- no
- Test temperature:
- 30°C
- Details on study design: HPLC method:
- EQUIPMENT
- Apparatus:Hewlett Packard 1050
- Type: Liquid Chromatograph
- Type, material and dimension of analytical (guard) column: Hypersil H5CPS (25 cm x 4.6 mm internal diameter)
- Detection system: UV set at 220 nm
MOBILE PHASES
- Type: Methanol:water (55:45 v/v)
- Experiments with additives carried out on separate columns: no
- pH:
- Solutes for dissolving test and reference substances:
DETERMINATION OF DEAD TIME
- Method: by means of homologous series / by inert substances which are not retained by the column
REFERENCE SUBSTANCES
- Identity: Acetanilide, Nitrobenzene, Naphthalene, 2-methylnaphthalene, Anthracene, DDT - Type:
- Koc
- Value:
- < 17.8
- Temp.:
- 30 °C
- Key result
- Type:
- log Koc
- Value:
- < 1.3
- Temp.:
- 30 °C
- Details on results (HPLC method):
- The value of logKoc of HEAA was found to be less than 1.3, as it's retention time was found to be less than that of the lowest run standard, acetanilide.
- Validity criteria fulfilled:
- yes
- Conclusions:
- HEAA was found to have a log10Koc value of less than 1.3 ( Koc less than 17.8).
- Executive summary:
The soil adsorption of this substance was determined using HPLC method based on OECD Guideline 121.
HEAA was found to have a logKoc value of less than 1.3 (Koc less than 17.8).
Reference
Description of key information
The soil adsorption of this substance was determined using HPLC method based on OECD Guideline 121.
HEAA was found to have a logKoc value of less than 1.3 (Koc less than 17.8).
Key value for chemical safety assessment
- Koc at 20 °C:
- 1.3
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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