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Diss Factsheets
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EC number: 700-169-7 | CAS number: 7646-67-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 21 June 2006 to 11 September 2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-A (Determination of the "Ready" Biodegradability - Dissolved Organic Carbon (DOC) Die-Away Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 A (Ready Biodegradability: DOC Die Away Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 835.3110 (Ready Biodegradability)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Lot number: 050804
Purity: >99.0% - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): The aeration tank at Worlingworth sewage treatment works, which treats predominantly domestic waste.
- Laboratory culture: Aliquots (25 ml) of a homegenised sample were filtered through dried and pre-weighed Whatman GF/C filter papers.
- Concentration of sludge: 30 mg/L
- Water filtered: yes
- Type and size of filter used, if any:Whatman GF/C - Duration of test (contact time):
- 28 d
- Initial conc.:
- 38.4 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- TEST SYSTEM
- Culturing apparatus: 2 L Erlenmeyer flasks
- Number of culture flasks/concentration: 3
SAMPLING
- Sampling frequency: samples (50 mL) were removed on days 0, 3, 5, 7, 10, 14, 21, 28 of the test
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes - Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 98.4
- Sampling time:
- 28 d
- Details on results:
- DOC removal by the mixtures containing HEAA was rapid and equivalent to 10% of the mean initial value by approximately day 5, 70% by day 8 and 97.7% after 10 days. A biodegradation plateau was considered achieved after 10 days.
- Results with reference substance:
- The mean level of biodegradation of sodium benzoate was 98.1% after 3 days. A biodegradation plateau was considered achieved after 3 days and the maximum level of degradation of the reference substance reached 100% on day 7.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- DOC removal by the test substance is greater than 70% within 28 days and this level reached within ten days of degradation reaching 10%. Hence, HEAA can be considered as readily biodegradable.
- Executive summary:
The ultimate biodegradability of HEAA was assessed in the DOC die-away test according to EU Method C4 and OECD Guideline 301A.
DOC removal by the test substance is greater than 70% within 28 days and this level reached within ten days of degradation reaching 10%. Hence, HEAA can be considered as readily biodegradable.
Reference
Description of key information
The ultimate biodegradability of HEAA was assessed in the DOC die-away test according to EU Method C4 and OECD Guideline 301A.
DOC removal by the test substance is greater than 70% within 28 days and this level reached within ten days of degradation reaching 10%. Hence, HEAA can be considered as readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.