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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: inherent biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2002
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study (OECD 302 B) but full details are not available. Therefore the reliability is with restricitions.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2002
Report date:
2002

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
7-methoxy-4,4-dimethyl-3,4-dihydro-1H-2-benzopyran-1,3-dione
EC Number:
611-342-0
Cas Number:
55974-25-9
Molecular formula:
C12 H12 O4
IUPAC Name:
7-methoxy-4,4-dimethyl-3,4-dihydro-1H-2-benzopyran-1,3-dione
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder
Details on test material:
- Name of test material (as cited in study report): Isochroman puro
- Physical state: powder
- Lot/batch No.: 01002

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
not specified
Duration of test (contact time):
28 d
Reference substance
Reference substance:
not specified

Results and discussion

% Degradation
Remarks on result:
other: Information on results see below in the field "Any other information on results incl. tables".

Any other information on results incl. tables

Days of measurement of DQO

Initial       7 days       14 days       21 days       28 day

White            5.0         7.0               13              6.0              4.0

Standard       693       640              458            448             399

DQO            544       520              544            593             548  

(mg/l O2)

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Interpretation of results:
under test conditions no biodegradation observed
Conclusions:
Owing the lack of response in the biodegradation of the product, a respirometry in a biological sewerage plant has been carried out, and it has been
proved and verified that Isochroman puro is not biodegradable.