7-(4-ethyl-1-methyloctyl)quinolin-8-ol

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

15 January - 22 January 2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

27 July 1995

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material:
Sponsor / 1702-18-01/O
- Expiration date of the lot/batch:
25 March 2021
- Purity test date:
26 March 2018

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material:
Room Temperature (20 ± 5 °C); Keep away from light
- Stability under test conditions:
Stable
- Solubility and stability of the test substance in the solvent/vehicle:
unknown

Key result

Boiling pt.:

323.85 °C

Atm. press.:

101 325 Pa

Decomposition:

yes

Decomp. temp.:

> 241.91 - < 378.96 °C

Values and observations

	Mass test item	Mass crucible (before measurement):	Mass crucible (after measurement):	Observations
First Measurement	3.45 mg	49.16 mg	45.75 mg	After the test the crucible was visually unchanged
Second Measurement	3.42 mg	49.52 mg	46.10 mg	After the test the crucible was visually unchanged
Third Measurement	3.29 mg	49.05 mg	45.86 mg	After the test the crucible was visually unchanged

Interpretation of the measurements

Based on the observations of the pre-test (darker colour, sunken baseline) the endotherm event should be indicated as boiling point under decomposition. The event was evaluated with onset function; the beginning and ending were evaluated with event marker function.

Results

For the calculation of the values of the mean and the standard deviation, only the second and third determination was taken into account.

Beginning boiling point under decomposition	in °C (event mark)	in K
1 Determination	241.91	515.06
2 Determination (not used for evaluation)	144.81	417.96
3 Determination	253.26	526.41
Min	241.91	515.06
Peak max	in °C	in K
1 Determination	362.11	635.26
2 Determination (not used for evaluation)	254.92	528.07
3 Determination	372.66	645.81
Onset boiling point under decomposition	in °C	in K
1 Determination	323.96	597.11
2 Determination (not used for evaluation)	226.82	499.97
3 Determination	323.73	596.88
Mean 1 and 3 Determination	323.85	597.00
sd	0.16	273.31
Ending boiling point under decomposition	in °C (event mark)	in K
1 Determination	373.07	646.22
2 Determination (not used for evaluation)	287.73	560.88
3 Determination	378.96	652.11
Max	378.96	652.11

Conclusions:

Based on the pre-test a boiling point under decomposition was determined under these circumstances as the endothermic event with:

The range of the event was detected with:
241.91 °C to 378.96 °C (515.06 K to 652.11 K),
with an onset of 323.85 °C (597.00 K) and a standard deviation of 0.16.

These values are the results from two independent (first and third determination) determinations.

Executive summary:

Findings and Results:

 

The boiling point was determined via DSC (differential scanning calorimetry)

 

Based on the pre-test a boiling point under decomposition was determined under these circumstances as the endothermic event with:

 

The range of the event was detected with:

241.91 °C to 378.96 °C (515.06 K to 652.11 K),

with an onset of 323.85 °C (597.00 K) and a standard deviation of 0.16.

 

These values are the results from two independent (first and third determination) determinations.

 

Description of key information

One key study was performed in accordance with OECD TG 103 and under the conditions of GLP.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

323.85 °C