Registration Dossier
Registration Dossier
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EC number: 241-734-3 | CAS number: 17741-63-8
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The test substance is with high probability not acutely harmful to fish. No toxic effects occur within the range of solubility.
Key value for chemical safety assessment
Additional information
A GLP guideline study according OECD 203 using zebrafish has been conducted (BASF SE 2015). Due to the low solubility of the test item a saturated solution has been prepared. The defined volume of test water was filled into the test vessel and an aliquot from the test water in the test vessel was taken and mixed with the test substance and the mixture was poured into the test vessel and the whole test batch was homogenized again. The test treatments were stirred for about 2 days to ensure that the saturated test solution was obtained. Undissolved test substance was not removed.
Moreover, concentration control analyses were not performed, because a reliable method for analyses in the required concentration range could not be developed. However, all reasonable efforts were taken to produce a saturated solution of the test substance in test media following the guidance in OECD 23 and the test fish were exposed to the entire loaded mass of test substance for the duration of the test. According to OECD 23, for tests with chemicals that cannot be quantified by analytical methods at the concentrations causing effects, the effect concentration can be expressed based on the nominal concentrations.
After 96 h no observable acute effect up to 100 mg/L in test media and under test conditions have been observed and the LC50 was determined to be > 100 mg/L. Therefore, no toxic effects occur within the range of solubility.
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