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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
other information
Study period:
2001
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Although the study has been conducted according to GLP guidelines, no final report was drafted. Based on the data summary alone it is difficult to establish whether GLP/OECD guidelines have been followed in detail.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2001
Report date:
2001

Materials and methods

GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
N-[3-(dimethylamino)propyl]acrylamide
EC Number:
223-342-4
EC Name:
N-[3-(dimethylamino)propyl]acrylamide
Cas Number:
3845-76-9
Molecular formula:
C8 H16 N2 O
IUPAC Name:
N‐[3‐(dimethylamino)propyl]prop‐2‐enamide

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
yes
Details on test solutions:
Kulturmedium für Testkulturen

Test organisms

Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Details on test organisms:
Common name: Green algae

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h

Test conditions

pH:
7.75 to 9.45
Nominal and measured concentrations:
Nominal: 1, 2, 4, 8, 16, 32, 64, 128 mg/L
Reference substance (positive control):
not specified

Results and discussion

Effect concentrationsopen allclose all
Duration:
72 h
Dose descriptor:
other: ErC50
Effect conc.:
> 128
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
other: ErC10
Effect conc.:
55 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
42
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
other: EbC50
Effect conc.:
22
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: AUGC: Area Under the Growth Curve
Duration:
72 h
Dose descriptor:
other: EbC10
Effect conc.:
11
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: AUGC: Area Under the Growth Curve
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
9.3
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: AUGC: Area Under the Growth Curve

Any other information on results incl. tables

 test substance nominal concentration (mg/L) control  1  2  4  8  16  32  64  128 
AUGC (% of control)  100  103  91  107  97  75  22  9  8 
growth rate (% of control)  100  110  105  112  115  132  115  85  62 

Applicant's summary and conclusion

Conclusions:
Growth rate inhibition:
IC50 > 128 mg/L
NOEC = 42 mg/L

AUGC:
IC50 = 22
NOEC = 9.3