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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Specific investigations: other studies

Currently viewing:

Administrative data

Endpoint:
biochemical or cellular interactions
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The origin and the purity of the test substance were known. The protocol and the results were described in details.

Data source

Reference
Reference Type:
publication
Title:
Effects of photbol myristate acetate, phorbol dibutyrate, ethanol, dimethylsulfoxide, phenol, and seven metabolites of phenol on metabolic cooperation between chinese hamster V79 lung fibroblasts
Author:
Malcolm A.R., Mills L.J., McKenna E.J.
Year:
1985
Bibliographic source:
Cell Biology and Toxicology, 1, 269-283.

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Guaiacol
EC Number:
201-964-7
EC Name:
Guaiacol
Cas Number:
90-05-1
Molecular formula:
C7H8O2
IUPAC Name:
Phenol
Details on test material:
Guaiacol was puchased from Fluka Chemical Corp, Hauppauge, NY and its purity was 98%.

Results and discussion

Any other information on results incl. tables

Guaiacol appeared to enhance metabolic cooperation.

Applicant's summary and conclusion