Registration Dossier
Registration Dossier
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EC number: 201-964-7 | CAS number: 90-05-1
Sediment toxicity
Administrative data
- Endpoint:
- sediment toxicity: short-term
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: No sufficient information was available to evaluate the validity of this study. No information was available about the test substance and the test conditions.
Data source
Reference
- Reference Type:
- publication
- Title:
- Effect of chlorinated phenol derivatives on various cell models
- Author:
- Cernakova M.
- Year:
- 1 994
- Bibliographic source:
- Folia Microbiol, 39(4): 315-320
Materials and methods
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Guaiacol
- EC Number:
- 201-964-7
- EC Name:
- Guaiacol
- Cas Number:
- 90-05-1
- Molecular formula:
- C7H8O2
- IUPAC Name:
- Phenol
- Details on test material:
- It was prepared at the Department of Wood, Pulp and Paper, Faculty of Chemical Technology, Slovak Technical University, Bratislava.
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test substrate
- Vehicle:
- yes
Test organisms
- Test organisms (species):
- Tubifex tubifex
Study design
- Study type:
- other: no data
- Test type:
- not specified
- Water media type:
- not specified
- Type of sediment:
- not specified
Exposure duration
- Duration:
- 45 min
- Exposure phase:
- total exposure duration
Test conditions
- Details on test conditions:
- The test substance was diluted in 1.4-dioxane at a concentration of 0.1 g/L. The test substance was evaluated versus the unaffected control, control with 1.4-dioxane, and the positive control represented by benzo[a]pyrene.
No complementary information was available about the test condition and the test design. - Reference substance (positive control):
- yes
- Remarks:
- benzo[a]pyrene
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 25 min
- Dose descriptor:
- LD50
- Effect conc.:
- 100 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 45 min
- Dose descriptor:
- LD100
- Effect conc.:
- 100 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Details on results:
- No mortality was observed in the control with 1.4-dioxane and in the control uninfluenced.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
