Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Data waiving:
other justification
Justification for data waiving:
other:

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Environmental Protection Agency: Toxic Substances Control Act Test Guidelines, Part 798-Health Effects Testing Guidelines, Subpart B, Section 798.1150, September 1985.
GLP compliance:
yes
Limit test:
yes

Test material

Constituent 1
Reference substance name:
Automatically generated during migration to IUCLID 6, no data available
IUPAC Name:
Automatically generated during migration to IUCLID 6, no data available
Details on test material:
Physical form of substance: S
Mass median aerodynamic diameter (for liq.+solid aerosol):
Equivalent Aerodynamic Diameter (mcm): 3.8

Test animals

Species:
other: Rat, Sprague-Dawley

Administration / exposure

Vehicle:
other: Air.
Details on inhalation exposure:
Whole body.
Duration of exposure:
4 h

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LC50
Effect level:
> 5 mg/L air
Exp. duration:
4 h
Mortality:
Male: 5 mg/L; Number of animals: 5; Number of deaths: 0
Female: 5 mg/L; Number of animals: 5; Number of deaths: 0
Clinical signs:
other: Signs of toxicity related to dose levels: The rats appeared normal before and just after exposure, but could not be observed during exposure due to the dense aerosol cloud within the chamber. All animals were normal in appearance throughout the post-e
Gross pathology:
Effects on organs:
No gross lesions were observed in any animals.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU