Registration Dossier
Registration Dossier
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EC number: 414-490-2 | CAS number: 154212-59-6
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11 April 1994 - 27 January 1995
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted according to Method A6 of the Commission Directive 92/69/EEC and in accordance with GLP. Study material is well characterised. Done under GLP and OECD method.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 995
- Report date:
- 1995
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes
- Type of method:
- flask method
- Remarks:
- Flask stirring method
Test material
- Reference substance name:
- -
- EC Number:
- 414-490-2
- EC Name:
- -
- Cas Number:
- 154212-59-6
- Molecular formula:
- C11H9ClN2O5S
- IUPAC Name:
- 4-nitrophenyl (1,3-thiazol-5-yl)methyl carbonate hydrochloride
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 0.3 g/L
- Temp.:
- 20 °C
- pH:
- > 1.59 - < 1.63
- Remarks on result:
- other: +/- 0.5 degrees Celcius
- Details on results:
- The water solubility determined by the bottle method at the temperature of 23ºC ± 1ºC is:
44.11 g/l or 44.11 mg/ml (44110 mg/l)
-- and the repeatability of these tests is 0.06% (it must be lower than 15%)
Any other information on results incl. tables
Water solubility was determined by HPLC to be 0.30 g/L at 20 degrees Celcius.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): moderately soluble (100-1000 mg/L)
Water solubility determined to be 0.30 g/L (304 mg/l) at 20 degrees Celcius, making it moderately soluble in water.
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