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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
grey literature
Title:
Pharmacological Properties of a New Diuretic: 5-Chloro-2,4-bis-Sulphonamidoaniline (Salamid)
Year:
1959
Bibliographic source:
Acta pharmacol. et toxicol. 1959, 15, 300-306
Report date:
1959

Materials and methods

Principles of method if other than guideline:
No data on method is available.
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
4-amino-6-chlorobenzene-1,3-disulphonamide
EC Number:
204-463-1
EC Name:
4-amino-6-chlorobenzene-1,3-disulphonamide
Cas Number:
121-30-2
Molecular formula:
C6H8ClN3O4S2
IUPAC Name:
4-amino-6-chlorobenzene-1,3-disulfonamide

Test animals

Species:
other: mouse and rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
about 10 g per kg bw

Results and discussion

Any other information on results incl. tables

The administered dose of 10 g/kg bw do not induce any signs of intoxication.

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information
Conclusions:
The acute toxicity of the substance is very low.