Registration Dossier

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Cross-referenceopen allclose all
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1991

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion)
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
standard quality material

Test animals

Species:
rabbit
Strain:
New Zealand White
Details on test animals and environmental conditions:
Information from migrated NONS file, as per inquiry 06-0000020508-70-0000, permission to refer granted by ECHA

Test system

Preparation of test site:
shaved
Vehicle:
unchanged (no vehicle)
Controls:
not required
Amount / concentration applied:
0.5g
Duration of treatment / exposure:
4 hours
Observation period:
0,24hrs,48hrs and 72 hrs.
Number of animals:
3

Results and discussion

In vivo

Irritant / corrosive response data:
no erythema or oedema observed in any animal at any observation stage.
Other effects:
no signs of any ill health or toxicity.

Any other information on results incl. tables

Information from migrated NONS file, as per inquiry 06-0000020508-70-0000, permission to refer granted by ECHA

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
A single semi-occlusive application of the testmaterial to intact rabbit skin elicited no dermal response.
Executive summary:

The test material is not classes a skin irritant.