Registration Dossier
Registration Dossier
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EC number: 700-676-3 | CAS number: 135452-42-5
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Test was conducted according to QSAR Modell Read-across from supporting substance (structure analogue or surrogate). Test substance (source substance): CAS No. 135452-43-6
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 014
- Report date:
- 2014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-hydroxy-1-{1-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,3,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one
- IUPAC Name:
- 2-hydroxy-1-{1-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,3,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one
- Reference substance name:
- 135452-43-6
- Cas Number:
- 135452-43-6
- IUPAC Name:
- 135452-43-6
- Reference substance name:
- 1-Propanone, 1-[2,3-dihydro-1-[4-(2-hydroxy-2-methyl-1-oxopropyl)phenyl]-1,3,3-trimethyl-1H-inden-5-yl]-2-hydroxy-2-methyl-
- IUPAC Name:
- 1-Propanone, 1-[2,3-dihydro-1-[4-(2-hydroxy-2-methyl-1-oxopropyl)phenyl]-1,3,3-trimethyl-1H-inden-5-yl]-2-hydroxy-2-methyl-
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Constituent 2
Constituent 3
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Total exposure duration:
- 48 h
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 493 000 000 mg/L
Any other information on results incl. tables
Log(LC50)= -6.08
LC50=4.93E8 mg/L
The substance falls to the “No Category” classification of GHS and this allows considering the toxicity as practically non-toxic.
Applicant's summary and conclusion
- Conclusions:
- The test substance was considered to be non-toxic to aquatic invertebrates (daphnia magna).
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