Registration Dossier
Registration Dossier
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EC number: 700-676-3 | CAS number: 135452-42-5
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Test was conducted according to OECD 301B resp. EU C.4.C and compliant with GLP. Read-across from supporting substance (structure analogue or surrogate). Test substance (source substance): CAS No. 135452-43-6
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-hydroxy-1-{1-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,3,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one
- IUPAC Name:
- 2-hydroxy-1-{1-[4-(2-hydroxy-2-methylpropanoyl)phenyl]-1,3,3-trimethyl-2,3-dihydro-1H-inden-5-yl}-2-methylpropan-1-one
- Reference substance name:
- 135452-43-6
- Cas Number:
- 135452-43-6
- IUPAC Name:
- 135452-43-6
- Reference substance name:
- 1-Propanone, 1-[2,3-dihydro-1-[4-(2-hydroxy-2-methyl-1-oxopropyl)phenyl]-1,3,3-trimethyl-1H-inden-5-yl]-2-hydroxy-2-methyl-
- IUPAC Name:
- 1-Propanone, 1-[2,3-dihydro-1-[4-(2-hydroxy-2-methyl-1-oxopropyl)phenyl]-1,3,3-trimethyl-1H-inden-5-yl]-2-hydroxy-2-methyl-
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Constituent 2
Constituent 3
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, adapted
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 26.1 mg/L
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 1.3
- Sampling time:
- 28 d
Any other information on results incl. tables
Degradation of the positive control was 67.2% after fourteen days.
The following data were determined for the test item:
10-day-window: not detected
degradation at the end of 10-day-window: none
degradation at the end of the test: 1.3%
pass level following guideline: 60% at the end of 10-day-window.
Since no 10-day-window was detected and degradation did not surpass 60% throughout the test, the test item is stated as not biodegradable within 28 days following OECD 301B/EU C.4.-C.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The test substance is not readily biodegradable.
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