Registration Dossier
Registration Dossier
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EC number: 606-080-9 | CAS number: 18637-00-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- December 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 2-ethoxybenzenecarboximidamide hydrochloride
- EC Number:
- 606-080-9
- Cas Number:
- 18637-00-8
- Molecular formula:
- C9 H12 N2 O . Cl H
- IUPAC Name:
- 2-ethoxybenzenecarboximidamide hydrochloride
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: particulates
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 72 h
Results and discussion
Effect concentrations
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 29.68 mg/L
- Nominal / measured:
- meas. (initial)
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Ethoxyamidin had an inhibitory effect on the growth rate of Desmosesmus subspicatus. THe EC50/72 h was 29.68 mg/L, the NOEC was 8.25 mg/L
- Executive summary:
Ethoxyamidin hydrochloris was studied in a growth inhibition test in the green algae Desmodesmus subspicatus. The algae were incubated to 3 concentrations: 0.825, 8.25 and 82.5 mg/L. The concentration was analyzed initially by TOC. Ethoxyamidin had n inhibitory effect on the test oranisms. The EC50 was detreminde wt 29.68 mg/L, the NOEC was 8.25 mg/L. Ethoxyamidin hydrochlorid is harmful to green algae.
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