Registration Dossier
Registration Dossier
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EC number: 939-448-5 | CAS number: 1469983-46-7
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The 96h LC50 of 2.14 mg/L (active ingredient) was determined in an acute toxicity test with Danio rerio according to OECD TG 203 under GLP conditions (Reliability 1).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 2.14 mg/L
Additional information
The acute toxicity to fish was performed in a study according to OECD TG 203 under GLP. The test was assigned reliability 1 as all validity criteria were fulfilled including complete identification of the test substance and chemical analysis of the test concentrations. The key study is based on the substance as registered: 3-(Isodecyloxy)propylamine acetate (CAS no 28701-67-9).
The key study was performed with Danio rerio under semi-static conditions using natural river water. The nominal test concentrations were 1.00 – 2.20 – 4.84 – 10.6 – and 23.4 mg/L. The measured concentrations of 3-(Isodecyloxy)propylamine acetate in freshly prepared media were in the range of 96 – 102 % and in 24 h aged test media in the range of 65 - 91 % of the nominal values, respectively. Results showed that round 1% of the 2.2 mg/L, sorbed to glassware in the test.
The LC50 (96 h) was calculated to be 2.20 mg/L based on the nominal concentration of the test material (96.2% active ingredient). The LC50 converted to active ingredient is 2.14 mg/L.
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